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      Emery Brown earns American Institute for Medical and Biological Engineering Pierre Galletti Award

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      The American Institute for Medical and Biological Engineering has awarded its highest honor this year to Emery N. Brown, the Edward Hood Taplin Professor of Computational Neuroscience and Health Sciences and Technology in The Picower Institute for Learning and Memory and the Institute for Medical Engineering and Science at MIT.

      Brown, who is also an anesthesiologist at Massachusetts General Hospital and the Warren M. Zapol Professor at Harvard Medical School, received the 2022 Pierre M. Galletti Award during the national organization’s Annual Event held on March 25.

      For decades, Brown’s lab has uniquely unified three fields: neuroscience, statistics, and anesthesiology. He is renowned for the development of statistical methods and signal-processing algorithms to enable and improve analysis of neural activity measurements. The work has had numerous applications including studies of learning and memory, brain-computer interfaces, and systems neuroscience. He has also pioneered investigations of how general anesthetic drugs work in the brain to induce and maintain simultaneous but reversible states of unconsciousness, amnesia, immobility, and analgesia. Building on these improvements in fundamental understanding, his lab engineers systems to improve monitoring of patient state and anesthetic dosing during surgery. Optimizing doses of general anesthetic drugs can improve patient care in many ways, including by minimizing side effects such as post-operative delirium and by improving post-operative pain management.

      AIMBE said Brown earned the award in recognition of his “significant contributions to neuroscience data analysis and for characterizing the neurophysiology of anesthesia-induced unconsciousness and demonstrating how it can be reliably monitored in real time using electroencephalogram recordings.”

      Brown, who is also a faculty member in MIT’s Department of Brain and Cognitive Sciences, is now working to develop a research center at MIT dedicated to taking neuroscience-based approaches to advance anesthesiology.

      “I am extremely honored and grateful to the AIMBE for choosing me to receive the 2022 Galletti Award in recognition of my research deciphering the neuroscience of how anesthetics work,” he says. “I would like to express my gratitude to my collaborators, post-doctoral fellows, students, research assistants, and clinical coordinators who have made this possible.” More

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      Devavrat Shah appointed faculty director of the Deshpande Center

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      Devavrat Shah, the Andrew (1956) and Erna Viterbi Professor in the Department of Electrical Engineering and Computer Science and the Institute for Data, Systems, and Society, has been named faculty director of the MIT Deshpande Center for Technological Innovations. The new role took effect on Feb. 1.

      Shah replaces Tim Swager, the John D. MacArthur Professor of Chemistry, who has held the position of faculty director since 2014. Working alongside Executive Director to the Deshpande Center Leon Sandler, Swager helped the Deshpande Center build an inclusive environment where innovation and entrepreneurship could thrive. By examining new models for directing, seeding, and fostering the commercialization of inventions and technology, Swager helped students and faculty breathe life into research, propelling it out of the lab and into the world as successful ventures.

      The MIT Deshpande Center for Technological Innovations is an interdepartmental center working to empower MIT’s most talented students and faculty by helping them bring new innovative technologies from the lab to the marketplace in the form of breakthrough products and new companies. Desh Deshpande founded the center with his wife, in 2002.

      “Professor Shah’s deep entrepreneurial experience coupled with his research on large complex networks will be tremendous assets to the center,” says Deshpande. “Devavrat is an impactful educator and inspiring mentor who will play a key role in the center’s mission to foster innovation and accelerate the impact of new discoveries.”

      Shah joined the Department of Electrical Engineering and Computer Science in 2005. With research focusing on statistical inference and stochastic networks, his research contributions span a variety of areas including resource allocation in communications networks, inference and learning on graphical models, algorithms for social data processing including ranking, recommendations and crowdsourcing, and more recently, causal inference using observational and experimental data.  

      While Shah’s work spans a range of areas across electrical engineering, computer science, and operations research, they are all tied together with the singular focus on developing algorithmic solutions for practical, challenging problems. He’s also authored two books, one on gossip algorithms in 2006 and the other on prediction methods of nearest neighbors in 2018. 

      A highly regarded teacher, Shah has been very active in curriculum development — most notably class 6.438 (Algorithms for Inference) and class 6.401 (Introduction to Statistical Data Analysis) — and has taken a leading role in developing educational programs in the statistics and data science at MIT as part of the Statistics and Data Science Center within the Institute for Data, Systems, and Society.

      “With his experience and contributions as a researcher, educator, and innovator, I have no doubt that Devavrat will excel as the next faculty director of the Deshpande Center and help usher in the next era of innovation for MIT,” says Anantha P. Chandrakasan, dean of the School of Engineering and Vannevar Bush Professor of Electrical Engineering and Computer Science. “I am grateful to Tim for the tremendous work he has done during his eight years as faculty director of the Deshpande Center. His commitment to building an inclusive environment for innovation and entrepreneurship to thrive was particularly impressive.” 

      A practiced entrepreneur, Shah co-founded Celect, Inc. — now part of Nike — in 2013, to help retailers accurately predict demand using omnichannel data. In 2019, he helped start IkigaiLabs, where he serves as CTO, with the mission to build self-driving organizations by enabling data-driven operations with human-in-the-loop with the ease of spreadsheet.

      Among his many achievements and accolades, Shah was named a Kavli Fellow of the National Academy of Science in 2014 and was just recently announced as an Institute of Electrical and Electronics Engineers (IEEE) Fellow for 2022. He’s also received a number of awards for his papers from INFORMS Applied Probability Society, INFORMS Management Science and Operations Management, NeurIPS, ACM Sigmetrics, and IEEE Infocom. His career prizes include the Erlang Prize from INFORMS Applied Probability Society and the Rising Star Award from ACM Sigmetrics. Shah has also received multiple Test of Time paper awards from ACM Sigmetrics and is recognized as a distinguished alumnus of his alma mater, the Indian Institute of Technology Bombay.

      “The Deshpande Center thanks Tim for his years of service as faculty director,” says the center’s executive director, Leon Sandler. “Tim’s commitment to innovation played an integral role in our success, and the center’s programs have thrived under his leadership. I look forward to working with Devavrat in the continuing effort to fulfill the mission of our center.”

      As part of his new post, Shah will work closely with Sandler, who has held the executive director position at the Deshpande Center since 2006. More

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      MIT Center for Real Estate launches the Asia Real Estate Initiative

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      To appreciate the explosive urbanization taking place in Asia, consider this analogy: Every 40 days, a city the equivalent size of Boston is built in Asia. Of the $24.7 trillion real estate investment opportunities predicted by 2030 in emerging cities, $17.8 trillion (72 percent) will be in Asia. While this growth is exciting to the real estate industry, it brings with it the attendant social and environmental issues.

      To promote a sustainable and innovative approach to this growth, leadership at the MIT Center for Real Estate (MIT CRE) recently established the Asia Real Estate Initiative (AREI), which aims to become a platform for industry leaders, entrepreneurs, and the academic community to find solutions to the practical concerns of real estate development across these countries.

      “Behind the creation of this initiative is the understanding that Asia is a living lab for the study of future global urban development,” says Hashim Sarkis, dean of the MIT School of Architecture and Planning.

      An investment in cities of the future

      One of the areas in AREI’s scope of focus is connecting sustainability and technology in real estate.

      “We believe the real estate sector should work cooperatively with the energy, science, and technology sectors to solve the climate challenges,” says Richard Lester, the Institute’s associate provost for international activities. “AREI will engage academics and industry leaders, nongovernment organizations, and civic leaders globally and in Asia, to advance sharing knowledge and research.”

      In its effort to understand how trends and new technologies will impact the future of real estate, AREI has received initial support from a prominent alumnus of MIT CRE who wishes to remain anonymous. The gift will support a cohort of researchers working on innovative technologies applicable to advancing real estate sustainability goals, with a special focus on the global and Asia markets. The call for applications is already under way, with AREI seeking to collaborate with scholars who have backgrounds in economics, finance, urban planning, technology, engineering, and other disciplines.

      “The research on real estate sustainability and technology could transform this industry and help invent global real estate of the future,” says Professor Siqi Zheng, faculty director of MIT CRE and AREI faculty chair. “The pairing of real estate and technology often leads to innovative and differential real estate development strategies such as buildings that are green, smart, and healthy.”

      The initiative arrives at a key time to make a significant impact and cement a leadership role in real estate development across Asia. MIT CRE is positioned to help the industry increase its efficiency and social responsibility, with nearly 40 years of pioneering research in the field. Zheng, an established scholar with expertise on urban growth in fast-urbanizing regions, is the former president of the Asia Real Estate Society and sits on the Board of American Real Estate and Urban Economics Association. Her research has been supported by international institutions including the World Bank, the Asian Development Bank, and the Lincoln Institute of Land Policy.

      “The researchers in AREI are now working on three interrelated themes: the future of real estate and live-work-play dynamics; connecting sustainability and technology in real estate; and innovations in real estate finance and business,” says Zheng.

      The first theme has already yielded a book — “Toward Urban Economic Vibrancy: Patterns and Practices in Asia’s New Cities” — recently published by SA+P Press.

      Engaging thought leaders and global stakeholders

      AREI also plans to collaborate with counterparts in Asia to contribute to research, education, and industry dialogue to meet the challenges of sustainable city-making across the continent and identify areas for innovation. Traditionally, real estate has been a very local business with a lengthy value chain, according to Zhengzhen Tan, director of AREI. Most developers focused their career on one particular product type in one particular regional market. AREI is working to change that dynamic.

      “We want to create a cross-border dialogue within Asia and among Asia, North America, and European leaders to exchange knowledge and practices,” says Tan. “The real estate industry’s learning costs are very high compared to other sectors. Collective learning will reduce the cost of failure and have a significant impact on these global issues.”

      The 2021 United Nations Climate Change Conference in Glasgow shed additional light on environmental commitments being made by governments in Asia. With real estate representing 40 percent of global greenhouse gas emissions, the Asian real estate market is undergoing an urgent transformation to deliver on this commitment.

      “One of the most pressing calls is to get to net-zero emissions for real estate development and operation,” says Tan. “Real estate investors and developers are making short- and long-term choices that are locking in environmental footprints for the ‘decisive decade.’ We hope to inspire developers and investors to think differently and get out of their comfort zone.” More

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      3 Questions: Fotini Christia on racial equity and data science

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      Fotini Christia is the Ford International Professor in the Social Sciences in the Department of Political Science, associate director of the Institute for Data, Systems, and Society (IDSS), and director of the Sociotechnical Systems Research Center (SSRC). Her research interests include issues of conflict and cooperation in the Muslim world, and she has conducted fieldwork in Afghanistan, Bosnia, Iran, the Palestinian Territories, Syria, and Yemen. She has co-organized the IDSS Research Initiative on Combatting Systemic Racism (ICSR), which works to bridge the social sciences, data science, and computation by bringing researchers from these disciplines together to address systemic racism across housing, health care, policing, education, employment, and other sectors of society.

      Q: What is the IDSS/ICSR approach to systemic racism research?

      A: The Research Initiative on Combatting Systemic Racism (ICSR) aims to seed and coordinate cross-disciplinary research to identify and overcome racially discriminatory processes and outcomes across a range of U.S. institutions and policy domains.

      Building off the extensive social science literature on systemic racism, the focus of this research initiative is to use big data to develop and harness computational tools that can help effect structural and normative change toward racial equity.

      The initiative aims to create a visible presence at MIT for cutting-edge computational research with a racial equity lens, across societal domains that will attract and train students and scholars.

      The steering committee for this research initiative is composed of underrepresented minority faculty members from across MIT’s five schools and the MIT Schwarzman College of Computing. Members will serve as close advisors to the initiative as well as share the findings of our work beyond MIT’s campus. MIT Chancellor Melissa Nobles heads this committee.

      Q: What role can data science play in helping to effect change toward racial equity?

      A: Existing work has shown racial discrimination in the job market, in the criminal justice system, as well as in education, health care, and access to housing, among other places. It has also underlined how algorithms could further entrench such bias — be it in training data or in the people who build them. Data science tools can not only help identify, but also contribute to, proposing fixes on racially inequitable outcomes that result from implicit or explicit biases in governing institutional practices in the public and private sector, and more recently from the use of AI and algorithmic methods in decision-making.

      To that effect, this initiative will produce research that explores and collects the relevant big data across domains, while paying attention to the ways such data are collected, and focus on improving and developing data-driven computational tools to address racial disparities in structures and institutions that have reproduced racially discriminatory outcomes in American society.

      The strong correlation between race, class, educational attainment, and various attitudes and behaviors in the American context can make it extremely difficult to rule out the influence of confounding factors. Thus, a key motivation for our research initiative is to highlight the importance of causal analysis using computational methods, and focus on understanding the opportunities of big data and algorithmic decision-making to address racial inequities and promote racial justice — beyond de-biasing algorithms. The intent is to also codify methodologies on equity-informed research practices and produce tools that are clear on the quantifiable expected social costs and benefits, as well as on the downstream effects on systemic racism more broadly.

      Q: What are some ways that the ICSR might conduct or follow-up on research seeking real-world impact or policy change?

      A: This type of research has ethical and societal considerations at its core, especially as they pertain to historically disadvantaged groups in the U.S., and will be coordinated with and communicated to local stakeholders to drive relevant policy decisions. This initiative intends to establish connections to URM [underrepresented minority] researchers and students at underrepresented universities and to directly collaborate with them on these research efforts. To that effect, we are leveraging existing programs such as the MIT Summer Research Program (MSRP).

      To ensure that our research targets the right problems bringing a racial equity lens with an interest to effect policy change, we will also connect with community organizations in minority neighborhoods who often bear the brunt of the direct and indirect effects of systemic racism, as well as with local government offices that work to address inequity in service provision in these communities. Our intent is to directly engage IDSS students with these organizations to help develop and test algorithmic tools for racial equity. More

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      Professor Emery Brown has big plans for anesthesiology

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      Emery N. Brown — the Edward Hood Taplin Professor of Medical Engineering and of Computational Neuroscience at MIT, an MIT professor of health sciences and technology, an investigator with The Picower Institute for Learning and Memory at MIT, and the Warren M. Zapol Professor of Anaesthesia at Harvard Medical School and Massachusetts General Hospital (MGH) — clearly excels at many roles. Renowned internationally for his anesthesia and neuroscience research, he embodies a unique blend of anesthesiologist, statistician, neuroscientist, educator, and mentor to both students and colleagues. Notably, Brown is one of the most decorated clinician-scientists in the country; he is one of only 25 people — and the first African-American, statistician, and anesthesiologist — to be elected to all three National Academies (Science, Engineering, and Medicine).

      Now, he is handing off one of his many key roles and responsibilities. After almost 10 years, Brown is stepping down as co-director of the Harvard-MIT Program in Health Sciences and Technology (HST). He will turn his energies toward working to develop a new joint center between MIT and MGH that uses the study of anesthesia to design novel approaches to controlling brain states. While a goal of the new center will be to improve anesthesia and intensive care unit management, according to Brown, it will also study related problems such as treating depression, insomnia, and epilepsy, as well as enhancing coma recovery.

      Founded in 1970, HST is one of the oldest interdisciplinary educational programs focused on training the next generation of clinician-scientists and engineers, who learn to translate science, engineering, and medical research into clinical practice, with the aim of improving human health. The MIT Institute for Medical Engineering and Science (IMES), where Brown is associate director, is HST’s home at MIT. Brown was the first HST co-director after the establishment of IMES in 2012; Wolfram Goessling is the Harvard University co-director of HST.

      “Emery has been an exemplary leader for HST during his tenure, and has helped it become a hub for the training of world-class scientists, engineers, and clinicians,” says Anantha Chandrakasan, dean of the MIT School of Engineering and the Vannevar Bush Professor of Electrical Engineering and Computer Science. “I am deeply grateful for his many years of service and wish him well as he moves on to new endeavors.”

      Elazer R. Edelman, director of IMES, calls Brown “a phenom who has been dedicated to our programs for years.”

      “With his thoughtful leadership and understated style, Emery made many contributions to the HST community,” Edelman continues. “On a personal note, this is bittersweet for me, as Emery has been a partner and mentor in my role as IMES director. And while I know that he will always be there for me, as he has been for all of us at IMES and HST, I will miss our late-night calls and midday conferences on matters of import for MIT, IMES, and HST.”

      Brown says “it was an honor and a privilege to co-direct HST with Wolfram.”

      “The students, staff, and faculty are simply amazing,” Brown continues. “Although, now more than 50 years old, HST remains at the vanguard for training PhD and MD students to work at the intersection between engineering, science, and medicine.”

      Goessling also thanks Brown for his leadership: “I truly valued Emery’s partnership and friendship, working together to deepen ties between the MIT and Harvard sides of HST. I am particularly grateful for working with Emery on our combined diversity efforts, leading to the HST Diversity Ambassadors initiative that made HST a better and stronger program.”

      According to Edelman, Brown was instrumental in the transition to new paradigms and relationships with HMS in the context of IMES. In 2014, he led the establishment of clear criteria for HST faculty membership, thereby strengthening the community of faculty experts who train students and provide research opportunities. More recently, he provided guidance through the turmoil of the ongoing Covid-19 pandemic, including the transition to online instruction and the return to the classroom. And Brown has always been a strong supporter of student diversity efforts, serving as an advocate and advisor to HST students.

      Brown holds BA, MA, and PhD degrees from Harvard University, and an MD from Harvard Medical School. He has been recognized with many awards, including the 2020 Swartz Prize in Theoretical and Computational Neuroscience, the 2018 Dickson Prize in Science, and an NIH Director’s Pioneer Award. Brown also served on President Barack Obama’s BRAIN Initiative Working Group. Among his many accomplishments, he has been cited for developing neural signal processing algorithms to characterize how neural systems represent and transmit information, and for unlocking the neurophysiology of how anesthetics produce the states of general anesthesia.

      Edelman says the process is underway to name a successor to Brown as co-director of HST at MIT. More

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      The downside of machine learning in health care

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      While working toward her dissertation in computer science at MIT, Marzyeh Ghassemi wrote several papers on how machine-learning techniques from artificial intelligence could be applied to clinical data in order to predict patient outcomes. “It wasn’t until the end of my PhD work that one of my committee members asked: ‘Did you ever check to see how well your model worked across different groups of people?’”

      That question was eye-opening for Ghassemi, who had previously assessed the performance of models in aggregate, across all patients. Upon a closer look, she saw that models often worked differently — specifically worse — for populations including Black women, a revelation that took her by surprise. “I hadn’t made the connection beforehand that health disparities would translate directly to model disparities,” she says. “And given that I am a visible minority woman-identifying computer scientist at MIT, I am reasonably certain that many others weren’t aware of this either.”

      In a paper published Jan. 14 in the journal Patterns, Ghassemi — who earned her doctorate in 2017 and is now an assistant professor in the Department of Electrical Engineering and Computer Science and the MIT Institute for Medical Engineering and Science (IMES) — and her coauthor, Elaine Okanyene Nsoesie of Boston University, offer a cautionary note about the prospects for AI in medicine. “If used carefully, this technology could improve performance in health care and potentially reduce inequities,” Ghassemi says. “But if we’re not actually careful, technology could worsen care.”

      It all comes down to data, given that the AI tools in question train themselves by processing and analyzing vast quantities of data. But the data they are given are produced by humans, who are fallible and whose judgments may be clouded by the fact that they interact differently with patients depending on their age, gender, and race, without even knowing it.

      Furthermore, there is still great uncertainty about medical conditions themselves. “Doctors trained at the same medical school for 10 years can, and often do, disagree about a patient’s diagnosis,” Ghassemi says. That’s different from the applications where existing machine-learning algorithms excel — like object-recognition tasks — because practically everyone in the world will agree that a dog is, in fact, a dog.

      Machine-learning algorithms have also fared well in mastering games like chess and Go, where both the rules and the “win conditions” are clearly defined. Physicians, however, don’t always concur on the rules for treating patients, and even the win condition of being “healthy” is not widely agreed upon. “Doctors know what it means to be sick,” Ghassemi explains, “and we have the most data for people when they are sickest. But we don’t get much data from people when they are healthy because they’re less likely to see doctors then.”

      Even mechanical devices can contribute to flawed data and disparities in treatment. Pulse oximeters, for example, which have been calibrated predominately on light-skinned individuals, do not accurately measure blood oxygen levels for people with darker skin. And these deficiencies are most acute when oxygen levels are low — precisely when accurate readings are most urgent. Similarly, women face increased risks during “metal-on-metal” hip replacements, Ghassemi and Nsoesie write, “due in part to anatomic differences that aren’t taken into account in implant design.” Facts like these could be buried within the data fed to computer models whose output will be undermined as a result.

      Coming from computers, the product of machine-learning algorithms offers “the sheen of objectivity,” according to Ghassemi. But that can be deceptive and dangerous, because it’s harder to ferret out the faulty data supplied en masse to a computer than it is to discount the recommendations of a single possibly inept (and maybe even racist) doctor. “The problem is not machine learning itself,” she insists. “It’s people. Human caregivers generate bad data sometimes because they are not perfect.”

      Nevertheless, she still believes that machine learning can offer benefits in health care in terms of more efficient and fairer recommendations and practices. One key to realizing the promise of machine learning in health care is to improve the quality of data, which is no easy task. “Imagine if we could take data from doctors that have the best performance and share that with other doctors that have less training and experience,” Ghassemi says. “We really need to collect this data and audit it.”

      The challenge here is that the collection of data is not incentivized or rewarded, she notes. “It’s not easy to get a grant for that, or ask students to spend time on it. And data providers might say, ‘Why should I give my data out for free when I can sell it to a company for millions?’ But researchers should be able to access data without having to deal with questions like: ‘What paper will I get my name on in exchange for giving you access to data that sits at my institution?’

      “The only way to get better health care is to get better data,” Ghassemi says, “and the only way to get better data is to incentivize its release.”

      It’s not only a question of collecting data. There’s also the matter of who will collect it and vet it. Ghassemi recommends assembling diverse groups of researchers — clinicians, statisticians, medical ethicists, and computer scientists — to first gather diverse patient data and then “focus on developing fair and equitable improvements in health care that can be deployed in not just one advanced medical setting, but in a wide range of medical settings.”

      The objective of the Patterns paper is not to discourage technologists from bringing their expertise in machine learning to the medical world, she says. “They just need to be cognizant of the gaps that appear in treatment and other complexities that ought to be considered before giving their stamp of approval to a particular computer model.” More

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      Professors Elchanan Mossel and Rosalind Picard named 2021 ACM Fellows

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      The Association for Computing Machinery (ACM) has named MIT professors Elchanan Mossel and Rosalind Picard as fellows for outstanding accomplishments in computing and information technology.

      The ACM Fellows program recognizes wide-ranging and fundamental contributions in areas including algorithms, computer science education, cryptography, data security and privacy, medical informatics, and mobile and networked systems, among many other areas. The accomplishments of the 2021 ACM Fellows underpin important innovations that shape the technologies we use every day.

      Elchanan Mossel

      Mossel is a professor of mathematics and a member at the Statistics and Data Science Center of the MIT Institute for Data, Systems and Society. His research in discrete functional inequalities, isoperimetry, and hypercontractivity led to the proof that Majority is Stablest and confirmed the optimality of the Goemans-Williamson MAX-CUT algorithm under the unique games conjecture from computational complexity. His work on the reconstruction problem on trees provides optimal algorithms and bounds for phylogenetic reconstruction in molecular biology and has led to sharp results in the analysis of Gibbs samplers from statistical physics and inference problems on graphs. His research has resolved open problems in computational biology, machine learning, social choice theory, and economics.Mossel received a BS from the Open University in Israel in 1992, and MS (1997) and PhD (2000) degrees in mathematics from the Hebrew University of Jerusalem. He was a postdoc at the Microsoft Research Theory Group and a Miller Fellow at University of California at Berkeley. He joined the UC Berkeley faculty in 2003 as a professor of statistics and computer science, and spent leaves as a professor at the Weizmann Institute and at the Wharton School before joining MIT in 2016 as a full professor.

      In 2020, he received the Vannevar Bush Faculty Fellowship of the U.S. Department of Defense. Other distinctions include being named a Simons Investigator in Mathematics in 2019, being selected as a fellow of the AMS, and receiving a Sloan Research Fellowship, NSF CAREER Award, and the Bergmann Memorial Award from the U.S.-Israel Binational Science Foundation.

      “I am honored by this award,” says Mossel. “It makes me realize how fortunate I’ve been, working with creative and generous colleagues, and mentoring brilliant young minds.”

      Rosalind Picard

      Picard is a scientist, engineer, author, and professor of media arts and sciences at the MIT Media Lab. She is recognized as the founder of the field of affective computing, and has carried this research forward as head of the Media Lab’s Affective Computing research group. She is also a founding faculty chair of MIT’s MindHandHeart Initiative, and a faculty member of the MIT Center for Neurobiological Engineering. Picard is an IEEE fellow, and a member of the National Academy of Engineering. 

      Picard’s inventions are in use by thousands of research teams worldwide as well as in numerous products and services. She has co-founded two companies: Affectiva (now part of Smart Eye), providing emotion AI technologies now used by more than 25 percent of the Global Fortune 500, and Empatica, providing wearable sensors and analytics to improve health. Starting from inventions by Picard and her team, Empatica created the first AI-based smart watch cleared by the FDA (in neurology for monitoring seizures), which is now helping to bring potentially lifesaving help for people with epilepsy. 

      “This award makes me think of how blessed I am to work with so many amazing people here at MIT, especially at the Media Lab,” Picard notes. “Whenever any one of us has our contributions recognized, it is also a recognition of how special a place this is.” More

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      The promise and pitfalls of artificial intelligence explored at TEDxMIT event

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      Scientists, students, and community members came together last month to discuss the promise and pitfalls of artificial intelligence at MIT’s Computer Science and Artificial Intelligence Laboratory (CSAIL) for the fourth TEDxMIT event held at MIT. 

      Attendees were entertained and challenged as they explored “the good and bad of computing,” explained CSAIL Director Professor Daniela Rus, who organized the event with John Werner, an MIT fellow and managing director of Link Ventures; MIT sophomore Lucy Zhao; and grad student Jessica Karaguesian. “As you listen to the talks today,” Rus told the audience, “consider how our world is made better by AI, and also our intrinsic responsibilities for ensuring that the technology is deployed for the greater good.”

      Rus mentioned some new capabilities that could be enabled by AI: an automated personal assistant that could monitor your sleep phases and wake you at the optimal time, as well as on-body sensors that monitor everything from your posture to your digestive system. “Intelligent assistance can help empower and augment our lives. But these intriguing possibilities should only be pursued if we can simultaneously resolve the challenges that these technologies bring,” said Rus. 

      The next speaker, CSAIL principal investigator and professor of electrical engineering and computer science Manolis Kellis, started off by suggesting what sounded like an unattainable goal — using AI to “put an end to evolution as we know it.” Looking at it from a computer science perspective, he said, what we call evolution is basically a brute force search. “You’re just exploring all of the search space, creating billions of copies of every one of your programs, and just letting them fight against each other. This is just brutal. And it’s also completely slow. It took us billions of years to get here.” Might it be possible, he asked, to speed up evolution and make it less messy?

      The answer, Kellis said, is that we can do better, and that we’re already doing better: “We’re not killing people like Sparta used to, throwing the weaklings off the mountain. We are truly saving diversity.”

      Knowledge, moreover, is now being widely shared, passed on “horizontally” through accessible information sources, he noted, rather than “vertically,” from parent to offspring. “I would like to argue that competition in the human species has been replaced by collaboration. Despite having a fixed cognitive hardware, we have software upgrades that are enabled by culture, by the 20 years that our children spend in school to fill their brains with everything that humanity has learned, regardless of which family came up with it. This is the secret of our great acceleration” — the fact that human advancement in recent centuries has vastly out-clipped evolution’s sluggish pace.

      The next step, Kellis said, is to harness insights about evolution in order to combat an individual’s genetic susceptibility to disease. “Our current approach is simply insufficient,” he added. “We’re treating manifestations of disease, not the causes of disease.” A key element in his lab’s ambitious strategy to transform medicine is to identify “the causal pathways through which genetic predisposition manifests. It’s only by understanding these pathways that we can truly manipulate disease causation and reverse the disease circuitry.” 

      Kellis was followed by Aleksander Madry, MIT professor of electrical engineering and computer science and CSAIL principal investigator, who told the crowd, “progress in AI is happening, and it’s happening fast.” Computer programs can routinely beat humans in games like chess, poker, and Go. So should we be worried about AI surpassing humans? 

      Madry, for one, is not afraid — or at least not yet. And some of that reassurance stems from research that has led him to the following conclusion: Despite its considerable success, AI, especially in the form of machine learning, is lazy. “Think about being lazy as this kind of smart student who doesn’t really want to study for an exam. Instead, what he does is just study all the past years’ exams and just look for patterns. Instead of trying to actually learn, he just tries to pass the test. And this is exactly the same way in which current AI is lazy.”

      A machine-learning model might recognize grazing sheep, for instance, simply by picking out pictures that have green grass in them. If a model is trained to identify fish from photos of anglers proudly displaying their catches, Madry explained, “the model figures out that if there’s a human holding something in the picture, I will just classify it as a fish.” The consequences can be more serious for an AI model intended to pick out malignant tumors. If the model is trained on images containing rulers that indicate the size of tumors, the model may end up selecting only those photos that have rulers in them.

      This leads to Madry’s biggest concerns about AI in its present form. “AI is beating us now,” he noted. “But the way it does it [involves] a little bit of cheating.” He fears that we will apply AI “in some way in which this mismatch between what the model actually does versus what we think it does will have some catastrophic consequences.” People relying on AI, especially in potentially life-or-death situations, need to be much more mindful of its current limitations, Madry cautioned.

      There were 10 speakers altogether, and the last to take the stage was MIT associate professor of electrical engineering and computer science and CSAIL principal investigator Marzyeh Ghassemi, who laid out her vision for how AI could best contribute to general health and well-being. But in order for that to happen, its models must be trained on accurate, diverse, and unbiased medical data.

      It’s important to focus on the data, Ghassemi stressed, because these models are learning from us. “Since our data is human-generated … a neural network is learning how to practice from a doctor. But doctors are human, and humans make mistakes. And if a human makes a mistake, and we train an AI from that, the AI will, too. Garbage in, garbage out. But it’s not like the garbage is distributed equally.”

      She pointed out that many subgroups receive worse care from medical practitioners, and members of these subgroups die from certain conditions at disproportionately high rates. This is an area, Ghassemi said, “where AI can actually help. This is something we can fix.” Her group is developing machine-learning models that are robust, private, and fair. What’s holding them back is neither algorithms nor GPUs. It’s data. Once we collect reliable data from diverse sources, Ghassemi added, we might start reaping the benefits that AI can bring to the realm of health care.

      In addition to CSAIL speakers, there were talks from members across MIT’s Institute for Data, Systems, and Society; the MIT Mobility Initiative; the MIT Media Lab; and the SENSEable City Lab.

      The proceedings concluded on that hopeful note. Rus and Werner then thanked everyone for coming. “Please continue to reflect about the good and bad of computing,” Rus urged. “And we look forward to seeing you back here in May for the next TEDxMIT event.”

      The exact theme of the spring 2022 gathering will have something to do with “superpowers.” But — if December’s mind-bending presentations were any indication — the May offering is almost certain to give its attendees plenty to think about. And maybe provide the inspiration for a startup or two. More