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    Advancing technology for aquaculture

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    According to the National Oceanic and Atmospheric Administration, aquaculture in the United States represents a $1.5 billion industry annually. Like land-based farming, shellfish aquaculture requires healthy seed production in order to maintain a sustainable industry. Aquaculture hatchery production of shellfish larvae — seeds — requires close monitoring to track mortality rates and assess health from the earliest stages of life. 

    Careful observation is necessary to inform production scheduling, determine effects of naturally occurring harmful bacteria, and ensure sustainable seed production. This is an essential step for shellfish hatcheries but is currently a time-consuming manual process prone to human error. 

    With funding from MIT’s Abdul Latif Jameel Water and Food Systems Lab (J-WAFS), MIT Sea Grant is working with Associate Professor Otto Cordero of the MIT Department of Civil and Environmental Engineering, Professor Taskin Padir and Research Scientist Mark Zolotas at the Northeastern University Institute for Experiential Robotics, and others at the Aquaculture Research Corporation (ARC), and the Cape Cod Commercial Fishermen’s Alliance, to advance technology for the aquaculture industry. Located on Cape Cod, ARC is a leading shellfish hatchery, farm, and wholesaler that plays a vital role in providing high-quality shellfish seed to local and regional growers.

    Two MIT students have joined the effort this semester, working with Robert Vincent, MIT Sea Grant’s assistant director of advisory services, through the Undergraduate Research Opportunities Program (UROP). 

    First-year student Unyime Usua and sophomore Santiago Borrego are using microscopy images of shellfish seed from ARC to train machine learning algorithms that will help automate the identification and counting process. The resulting user-friendly image recognition tool aims to aid aquaculturists in differentiating and counting healthy, unhealthy, and dead shellfish larvae, improving accuracy and reducing time and effort.

    Vincent explains that AI is a powerful tool for environmental science that enables researchers, industry, and resource managers to address challenges that have long been pinch points for accurate data collection, analysis, predictions, and streamlining processes. “Funding support from programs like J-WAFS enable us to tackle these problems head-on,” he says. 

    ARC faces challenges with manually quantifying larvae classes, an important step in their seed production process. “When larvae are in their growing stages they are constantly being sized and counted,” explains Cheryl James, ARC larval/juvenile production manager. “This process is critical to encourage optimal growth and strengthen the population.” 

    Developing an automated identification and counting system will help to improve this step in the production process with time and cost benefits. “This is not an easy task,” says Vincent, “but with the guidance of Dr. Zolotas at the Northeastern University Institute for Experiential Robotics and the work of the UROP students, we have made solid progress.” 

    The UROP program benefits both researchers and students. Involving MIT UROP students in developing these types of systems provides insights into AI applications that they might not have considered, providing opportunities to explore, learn, and apply themselves while contributing to solving real challenges.

    Borrego saw this project as an opportunity to apply what he’d learned in class 6.390 (Introduction to Machine Learning) to a real-world issue. “I was starting to form an idea of how computers can see images and extract information from them,” he says. “I wanted to keep exploring that.”

    Usua decided to pursue the project because of the direct industry impacts it could have. “I’m pretty interested in seeing how we can utilize machine learning to make people’s lives easier. We are using AI to help biologists make this counting and identification process easier.” While Usua wasn’t familiar with aquaculture before starting this project, she explains, “Just hearing about the hatcheries that Dr. Vincent was telling us about, it was unfortunate that not a lot of people know what’s going on and the problems that they’re facing.”

    On Cape Cod alone, aquaculture is an $18 million per year industry. But the Massachusetts Division of Marine Fisheries estimates that hatcheries are only able to meet 70–80 percent of seed demand annually, which impacts local growers and economies. Through this project, the partners aim to develop technology that will increase seed production, advance industry capabilities, and help understand and improve the hatchery microbiome.

    Borrego explains the initial challenge of having limited data to work with. “Starting out, we had to go through and label all of the data, but going through that process helped me learn a lot.” In true MIT fashion, he shares his takeaway from the project: “Try to get the best out of what you’re given with the data you have to work with. You’re going to have to adapt and change your strategies depending on what you have.”

    Usua describes her experience going through the research process, communicating in a team, and deciding what approaches to take. “Research is a difficult and long process, but there is a lot to gain from it because it teaches you to look for things on your own and find your own solutions to problems.”

    In addition to increasing seed production and reducing the human labor required in the hatchery process, the collaborators expect this project to contribute to cost savings and technology integration to support one of the most underserved industries in the United States. 

    Borrego and Usua both plan to continue their work for a second semester with MIT Sea Grant. Borrego is interested in learning more about how technology can be used to protect the environment and wildlife. Usua says she hopes to explore more projects related to aquaculture. “It seems like there’s an infinite amount of ways to tackle these issues.” More

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      Growing our donated organ supply

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      For those in need of one, an organ transplant is a matter of life and death. 

      Every year, the medical procedure gives thousands of people with advanced or end-stage diseases extended life. This “second chance” is heavily dependent on the availability, compatibility, and proximity of a precious resource that can’t be simply bought, grown, or manufactured — at least not yet.

      Instead, organs must be given — cut from one body and implanted into another. And because living organ donation is only viable in certain cases, many organs are only available for donation after the donor’s death.

      Unsurprisingly, the logistical and ethical complexity of distributing a limited number of transplant organs to a growing wait list of patients has received much attention. There’s an important part of the process that has received less focus, however, and which may hold significant untapped potential: organ procurement itself.

      “If you have a donated organ, who should you give it to? This question has been extensively studied in operations research, economics, and even applied computer science,” says Hammaad Adam, a graduate student in the Social and Engineering Systems (SES) doctoral program at the MIT Institute for Data, Systems, and Society (IDSS). “But there’s been a lot less research on where that organ comes from in the first place.”

      In the United States, nonprofits called organ procurement organizations, or OPOs, are responsible for finding and evaluating potential donors, interacting with grieving families and hospital administrations, and recovering and delivering organs — all while following the federal laws that serve as both their mandate and guardrails. Recent studies estimate that obstacles and inefficiencies lead to thousands of organs going uncollected every year, even as the demand for transplants continues to grow.

      “There’s been little transparent data on organ procurement,” argues Adam. Working with MIT computer science professors Marzyeh Ghassemi and Ashia Wilson, and in collaboration with stakeholders in organ procurement, Adam led a project to create a dataset called ORCHID: Organ Retrieval and Collection of Health Information for Donation. ORCHID contains a decade of clinical, financial, and administrative data from six OPOs.

      “Our goal is for the ORCHID database to have an impact in how organ procurement is understood, internally and externally,” says Ghassemi.

      Efficiency and equity 

      It was looking to make an impact that drew Adam to SES and MIT. With a background in applied math and experience in strategy consulting, solving problems with technical components sits right in his wheelhouse.

      “I really missed challenging technical problems from a statistics and machine learning standpoint,” he says of his time in consulting. “So I went back and got a master’s in data science, and over the course of my master’s got involved in a bunch of academic research projects in a few different fields, including biology, management science, and public policy. What I enjoyed most were some of the more social science-focused projects that had immediate impact.”

      As a grad student in SES, Adam’s research focuses on using statistical tools to uncover health-care inequities, and developing machine learning approaches to address them. “Part of my dissertation research focuses on building tools that can improve equity in clinical trials and other randomized experiments,” he explains.

      One recent example of Adam’s work: developing a novel method to stop clinical trials early if the treatment has an unintended harmful effect for a minority group of participants. “I’ve also been thinking about ways to increase minority representation in clinical trials through improved patient recruitment,” he adds.

      Racial inequities in health care extend into organ transplantation, where a majority of wait-listed patients are not white — far in excess of their demographic groups’ proportion to the overall population. There are fewer organ donations from many of these communities, due to various obstacles in need of better understanding if they are to be overcome. 

      “My work in organ transplantation began on the allocation side,” explains Adam. “In work under review, we examined the role of race in the acceptance of heart, liver, and lung transplant offers by physicians on behalf of their patients. We found that Black race of the patient was associated with significantly lower odds of organ offer acceptance — in other words, transplant doctors seemed more likely to turn down organs offered to Black patients. This trend may have multiple explanations, but it is nevertheless concerning.”

      Adam’s research has also found that donor-candidate race match was associated with significantly higher odds of offer acceptance, an association that Adam says “highlights the importance of organ donation from racial minority communities, and has motivated our work on equitable organ procurement.”

      Working with Ghassemi through the IDSS Initiative on Combatting Systemic Racism, Adam was introduced to OPO stakeholders looking to collaborate. “It’s this opportunity to impact not only health-care efficiency, but also health-care equity, that really got me interested in this research,” says Adam.

      Play video

      MIT Initiative on Combatting Systemic Racism – HealthcareVideo: IDSS

      Making an impact

      Creating a database like ORCHID means solving problems in multiple domains, from the technical to the political. Some efforts never overcome the first step: getting data in the first place. Thankfully, several OPOs were already seeking collaborations and looking to improve their performance.

      “We have been lucky to have a strong partnership with the OPOs, and we hope to work together to find important insights to improve efficiency and equity,” says Ghassemi.

      The value of a database like ORCHID is in its potential for generating new insights, especially through quantitative analysis with statistics and computing tools like machine learning. The potential value in ORCHID was recognized with an MIT Prize for Open Data, an MIT Libraries award highlighting the importance and impact of research data that is openly shared.

      “It’s nice that the work got some recognition,” says Adam of the prize. “And it was cool to see some of the other great open data work that’s happening at MIT. I think there’s real impact in releasing publicly available data in an important and understudied domain.”

      All the same, Adam knows that building the database is only the first step.

      “I’m very interested in understanding the bottlenecks in the organ procurement process,” he explains. “As part of my thesis research, I’m exploring this by modeling OPO decision-making using causal inference and structural econometrics.”

      Using insights from this research, Adam also aims to evaluate policy changes that can improve both equity and efficiency in organ procurement. “And we’re hoping to recruit more OPOs, and increase the amount of data we’re releasing,” he says. “The dream state is every OPO joins our collaboration and provides updated data every year.”

      Adam is excited to see how other researchers might use the data to address inefficiencies in organ procurement. “Every organ donor saves between three and four lives,” he says. “So every research project that comes out of this dataset could make a real impact.” More

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      in Data Management & Statistics

      Q&A: How refusal can be an act of design

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      This month in the ACM Journal on Responsible Computing, MIT graduate student Jonathan Zong SM ’20 and co-author J. Nathan Matias SM ’13, PhD ’17 of the Cornell Citizens and Technology Lab examine how the notion of refusal can open new avenues in the field of data ethics. In their open-access report, “Data Refusal From Below: A Framework for Understanding, Evaluating, and Envisioning Refusal as Design,” the pair proposes a framework in four dimensions to map how individuals can say “no” to technology misuses. At the same time, the researchers argue that just like design, refusal is generative, and has the potential to create alternate futures.

      Zong, a PhD candidate in electrical engineering and computer science, 2022-23 MIT Morningside Academy for Design Design Fellow, and member of the MIT Visualization Group, describes his latest work in this Q&A.

      Q: How do you define the concept of “refusal,” and where does it come from?

      A: Refusal was developed in feminist and Indigenous studies. It’s this idea of saying “no,” without being given permission to say “no.” Scholars like Ruha Benjamin write about refusal in the context of surveillance, race, and bioethics, and talk about it as a necessary counterpart to consent. Others, like the authors of the “Feminist Data Manifest-No,” think of refusal as something that can help us commit to building better futures.

      Benjamin illustrates cases where the choice to refuse is not equally possible for everyone, citing examples involving genetic data and refugee screenings in the U.K. The imbalance of power in these situations underscores the broader concept of refusal, extending beyond rejecting specific options to challenging the entire set of choices presented.

      Q: What inspired you to work on the notion of refusal as an act of design?

      A: In my work on data ethics, I’ve been thinking about how to incorporate processes into research data collection, particularly around consent and opt-out, with a focus on individual autonomy and the idea of giving people choices about the way that their data is used. But when it comes to data privacy, simply making choices available is not enough. Choices can be unequally available, or create no-win situations where all options are bad. This led me to the concept of refusal: questioning the authority of data collectors and challenging their legitimacy.

      The key idea of my work is that refusal is an act of design. I think of refusal as deliberate actions to redesign our socio-technical landscape by exerting some sort of influence. Like design, refusal is generative. Like design, it’s oriented towards creating alternate possibilities and alternate futures. Design is a process of exploring or traversing a space of possibility. Applying a design framework to cases of refusal drawn from scholarly and journalistic sources allowed me to establish a common language for talking about refusal and to imagine refusals that haven’t been explored yet.

      Q: What are the stakes around data privacy and data collection?

      A: The use of data for facial recognition surveillance in the U.S. is a big example we use in the paper. When people do everyday things like post on social media or walk past cameras in public spaces, they might be contributing their data to training facial recognition systems. For instance, a tech company may take photos from a social media site and build facial recognition that they then sell to the government. In the U.S., these systems are disproportionately used by police to surveil communities of color. It is difficult to apply concepts like consent and opt out of these processes, because they happen over time and involve multiple kinds of institutions. It’s also not clear that individual opt-out would do anything to change the overall situation. Refusal then becomes a crucial avenue, at both individual and community levels, to think more broadly of how affected people still exert some kind of voice or agency, without necessarily having an official channel to do so.

      Q: Why do you think these issues are more particularly affecting disempowered communities?

      A: People who are affected by technologies are not always included in the design process for those technologies. Refusal then becomes a meaningful expression of values and priorities for those who were not part of the early design conversations. Actions taken against technologies like face surveillance — be it legal battles against companies, advocacy for stricter regulations, or even direct action like disabling security cameras — may not fit the conventional notion of participating in a design process. And yet, these are the actions available to refusers who may be excluded from other forms of participation.

      I’m particularly inspired by the movement around Indigenous data sovereignty. Organizations like the First Nations Information Governance Centre work towards prioritizing Indigenous communities’ perspectives in data collection, and refuse inadequate representation in official health data from the Canadian government. I think this is a movement that exemplifies the potential of refusal, not only as a way to reject what’s being offered, but also as a means to propose a constructive alternative, very much like design. Refusal is not merely a negation, but a pathway to different futures.

      Q: Can you elaborate on the design framework you propose?

      A: Refusals vary widely across contexts and scales. Developing a framework for refusal is about helping people see actions that are seemingly very different as instances of the same broader idea. Our framework consists of four facets: autonomy, time, power, and cost.

      Consider the case of IBM creating a facial recognition dataset using people’s photos without consent. We saw multiple forms of refusal emerge in response. IBM allowed individuals to opt out by withdrawing their photos. People collectively refused by creating a class-action lawsuit against IBM. Around the same time, many U.S. cities started passing local legislation banning the government use of facial recognition. Evaluating these cases through the framework highlights commonalities and differences. The framework highlights varied approaches to autonomy, like individual opt-out and collective action. Regarding time, opt-outs and lawsuits react to past harm, while legislation might proactively prevent future harm. Power dynamics differ; withdrawing individual photos minimally influences IBM, while legislation could potentially cause longer-term change. And as for cost, individual opt-out seems less demanding, while other approaches require more time and effort, balanced against potential benefits.

      The framework facilitates case description and comparison across these dimensions. I think its generative nature encourages exploration of novel forms of refusal as well. By identifying the characteristics we want to see in future refusal strategies — collective, proactive, powerful, low-cost… — we can aspire to shape future approaches and change the behavior of data collectors. We may not always be able to combine all these criteria, but the framework provides a means to articulate our aspirational goals in this context.

      Q: What impact do you hope this research will have?

      A: I hope to expand the notion of who can participate in design, and whose actions are seen as legitimate expressions of design input. I think a lot of work so far in the conversation around data ethics prioritizes the perspective of computer scientists who are trying to design better systems, at the expense of the perspective of people for whom the systems are not currently working. So, I hope designers and computer scientists can embrace the concept of refusal as a legitimate form of design, and a source of inspiration. There’s a vital conversation happening, one that should influence the design of future systems, even if expressed through unconventional means.

      One of the things I want to underscore in the paper is that design extends beyond software. Taking a socio-technical perspective, the act of designing encompasses software, institutions, relationships, and governance structures surrounding data use. I want people who aren’t software engineers, like policymakers or activists, to view themselves as integral to the technology design process. More

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      Six MIT students selected as spring 2024 MIT-Pillar AI Collective Fellows

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      The MIT-Pillar AI Collective has announced six fellows for the spring 2024 semester. With support from the program, the graduate students, who are in their final year of a master’s or PhD program, will conduct research in the areas of AI, machine learning, and data science with the aim of commercializing their innovations.

      Launched by MIT’s School of Engineering and Pillar VC in 2022, the MIT-Pillar AI Collective supports faculty, postdocs, and students conducting research on AI, machine learning, and data science. Supported by a gift from Pillar VC and administered by the MIT Deshpande Center for Technological Innovation, the mission of the program is to advance research toward commercialization.

      The spring 2024 MIT-Pillar AI Collective Fellows are:

      Yasmeen AlFaraj

      Yasmeen AlFaraj is a PhD candidate in chemistry whose interest is in the application of data science and machine learning to soft materials design to enable next-generation, sustainable plastics, rubber, and composite materials. More specifically, she is applying machine learning to the design of novel molecular additives to enable the low-cost manufacturing of chemically deconstructable thermosets and composites. AlFaraj’s work has led to the discovery of scalable, translatable new materials that could address thermoset plastic waste. As a Pillar Fellow, she will pursue bringing this technology to market, initially focusing on wind turbine blade manufacturing and conformal coatings. Through the Deshpande Center for Technological Innovation, AlFaraj serves as a lead for a team developing a spinout focused on recyclable versions of existing high-performance thermosets by incorporating small quantities of a degradable co-monomer. In addition, she participated in the National Science Foundation Innovation Corps program and recently graduated from the Clean Tech Open, where she focused on enhancing her business plan, analyzing potential markets, ensuring a complete IP portfolio, and connecting with potential funders. AlFaraj earned a BS in chemistry from University of California at Berkeley.

      Ruben Castro Ornelas

      Ruben Castro Ornelas is a PhD student in mechanical engineering who is passionate about the future of multipurpose robots and designing the hardware to use them with AI control solutions. Combining his expertise in programming, embedded systems, machine design, reinforcement learning, and AI, he designed a dexterous robotic hand capable of carrying out useful everyday tasks without sacrificing size, durability, complexity, or simulatability. Ornelas’s innovative design holds significant commercial potential in domestic, industrial, and health-care applications because it could be adapted to hold everything from kitchenware to delicate objects. As a Pillar Fellow, he will focus on identifying potential commercial markets, determining the optimal approach for business-to-business sales, and identifying critical advisors. Ornelas served as co-director of StartLabs, an undergraduate entrepreneurship club at MIT, where he earned an BS in mechanical engineering.

      Keeley Erhardt

      Keeley Erhardt is a PhD candidate in media arts and sciences whose research interests lie in the transformative potential of AI in network analysis, particularly for entity correlation and hidden link detection within and across domains. She has designed machine learning algorithms to identify and track temporal correlations and hidden signals in large-scale networks, uncovering online influence campaigns originating from multiple countries. She has similarly demonstrated the use of graph neural networks to identify coordinated cryptocurrency accounts by analyzing financial time series data and transaction dynamics. As a Pillar Fellow, Erhardt will pursue the potential commercial applications of her work, such as detecting fraud, propaganda, money laundering, and other covert activity in the finance, energy, and national security sectors. She has had internships at Google, Facebook, and Apple and held software engineering roles at multiple tech unicorns. Erhardt earned an MEng in electrical engineering and computer science and a BS in computer science, both from MIT.

      Vineet Jagadeesan Nair

      Vineet Jagadeesan Nair is a PhD candidate in mechanical engineering whose research focuses on modeling power grids and designing electricity markets to integrate renewables, batteries, and electric vehicles. He is broadly interested in developing computational tools to tackle climate change. As a Pillar Fellow, Nair will explore the application of machine learning and data science to power systems. Specifically, he will experiment with approaches to improve the accuracy of forecasting electricity demand and supply with high spatial-temporal resolution. In collaboration with Project Tapestry @ Google X, he is also working on fusing physics-informed machine learning with conventional numerical methods to increase the speed and accuracy of high-fidelity simulations. Nair’s work could help realize future grids with high penetrations of renewables and other clean, distributed energy resources. Outside academics, Nair is active in entrepreneurship, most recently helping to organize the 2023 MIT Global Startup Workshop in Greece. He earned an MS in computational science and engineering from MIT, an MPhil in energy technologies from Cambridge University as a Gates Scholar, and a BS in mechanical engineering and a BA in economics from University of California at Berkeley.

      Mahdi Ramadan

      Mahdi Ramadan is a PhD candidate in brain and cognitive sciences whose research interests lie at the intersection of cognitive science, computational modeling, and neural technologies. His work uses novel unsupervised methods for learning and generating interpretable representations of neural dynamics, capitalizing on recent advances in AI, specifically contrastive and geometric deep learning techniques capable of uncovering the latent dynamics underlying neural processes with high fidelity. As a Pillar Fellow, he will leverage these methods to gain a better understanding of dynamical models of muscle signals for generative motor control. By supplementing current spinal prosthetics with generative AI motor models that can streamline, speed up, and correct limb muscle activations in real time, as well as potentially using multimodal vision-language models to infer the patients’ high-level intentions, Ramadan aspires to build truly scalable, accessible, and capable commercial neuroprosthetics. Ramadan’s entrepreneurial experience includes being the co-founder of UltraNeuro, a neurotechnology startup, and co-founder of Presizely, a computer vision startup. He earned a BS in neurobiology from University of Washington.

      Rui (Raymond) Zhou

      Rui (Raymond) Zhou is a PhD candidate in mechanical engineering whose research focuses on multimodal AI for engineering design. As a Pillar Fellow, he will advance models that could enable designers to translate information in any modality or combination of modalities into comprehensive 2D and 3D designs, including parametric data, component visuals, assembly graphs, and sketches. These models could also optimize existing human designs to accomplish goals such as improving ergonomics or reducing drag coefficient. Ultimately, Zhou aims to translate his work into a software-as-a-service platform that redefines product design across various sectors, from automotive to consumer electronics. His efforts have the potential to not only accelerate the design process but also reduce costs, opening the door to unprecedented levels of customization, idea generation, and rapid prototyping. Beyond his academic pursuits, Zhou founded UrsaTech, a startup that integrates AI into education and engineering design. He earned a BS in electrical engineering and computer sciences from University of California at Berkeley. More

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      Creating new skills and new connections with MIT’s Quantitative Methods Workshop

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      Starting on New Year’s Day, when many people were still clinging to holiday revelry, scores of students and faculty members from about a dozen partner universities instead flipped open their laptops for MIT’s Quantitative Methods Workshop, a jam-packed, weeklong introduction to how computational and mathematical techniques can be applied to neuroscience and biology research. But don’t think of QMW as a “crash course.” Instead the program’s purpose is to help elevate each participant’s scientific outlook, both through the skills and concepts it imparts and the community it creates.

      “It broadens their horizons, it shows them significant applications they’ve never thought of, and introduces them to people whom as researchers they will come to know and perhaps collaborate with one day,” says Susan L. Epstein, a Hunter College computer science professor and education coordinator of MIT’s Center for Brains, Minds, and Machines, which hosts the program with the departments of Biology and Brain and Cognitive Sciences and The Picower Institute for Learning and Memory. “It is a model of interdisciplinary scholarship.”

      This year 83 undergraduates and faculty members from institutions that primarily serve groups underrepresented in STEM fields took part in the QMW, says organizer Mandana Sassanfar, senior lecturer and director of diversity and science outreach across the four hosting MIT entities. Since the workshop launched in 2010, it has engaged more than 1,000 participants, of whom more than 170 have gone on to participate in MIT Summer Research Programs (such as MSRP-BIO), and 39 have come to MIT for graduate school.

      Individual goals, shared experience

      Undergraduates and faculty in various STEM disciplines often come to QMW to gain an understanding of, or expand their expertise in, computational and mathematical data analysis. Computer science- and statistics-minded participants come to learn more about how such techniques can be applied in life sciences fields. In lectures; in hands-on labs where they used the computer programming language Python to process, analyze, and visualize data; and in less formal settings such as tours and lunches with MIT faculty, participants worked and learned together, and informed each other’s perspectives.

      Brain and Cognitive Sciences Professor Nancy Kanwisher delivers a lecture in MIT’s Building 46 on functional brain imaging to QMW participants.

      Photo: Mandana Sassanfar

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      And regardless of their field of study, participants made connections with each other and with the MIT students and faculty who taught and spoke over the course of the week.

      Hunter College computer science sophomore Vlad Vostrikov says that while he has already worked with machine learning and other programming concepts, he was interested to “branch out” by seeing how they are used to analyze scientific datasets. He also valued the chance to learn the experiences of the graduate students who teach QMW’s hands-on labs.

      “This was a good way to explore computational biology and neuroscience,” Vostrikov says. “I also really enjoy hearing from the people who teach us. It’s interesting to hear where they come from and what they are doing.”

      Jariatu Kargbo, a biology and chemistry sophomore at University of Maryland Baltimore County, says when she first learned of the QMW she wasn’t sure it was for her. It seemed very computation-focused. But her advisor Holly Willoughby encouraged Kargbo to attend to learn about how programming could be useful in future research — currently she is taking part in research on the retina at UMBC. More than that, Kargbo also realized it would be a good opportunity to make connections at MIT in advance of perhaps applying for MSRP this summer.

      “I thought this would be a great way to meet up with faculty and see what the environment is like here because I’ve never been to MIT before,” Kargbo says. “It’s always good to meet other people in your field and grow your network.”

      QMW is not just for students. It’s also for their professors, who said they can gain valuable professional education for their research and teaching.

      Fayuan Wen, an assistant professor of biology at Howard University, is no stranger to computational biology, having performed big data genetic analyses of sickle cell disease (SCD). But she’s mostly worked with the R programming language and QMW’s focus is on Python. As she looks ahead to projects in which she wants analyze genomic data to help predict disease outcomes in SCD and HIV, she says a QMW session delivered by biology graduate student Hannah Jacobs was perfectly on point.

      “This workshop has the skills I want to have,” Wen says.

      Moreover, Wen says she is looking to start a machine-learning class in the Howard biology department and was inspired by some of the teaching materials she encountered at QMW — for example, online curriculum modules developed by Taylor Baum, an MIT graduate student in electrical engineering and computer science and Picower Institute labs, and Paloma Sánchez-Jáuregui, a coordinator who works with Sassanfar.

      Tiziana Ligorio, a Hunter College computer science doctoral lecturer who together with Epstein teaches a deep machine-learning class at the City University of New York campus, felt similarly. Rather than require a bunch of prerequisites that might drive students away from the class, Ligorio was looking to QMW’s intense but introductory curriculum as a resource for designing a more inclusive way of getting students ready for the class.

      Instructive interactions

      Each day runs from 9 a.m. to 5 p.m., including morning and afternoon lectures and hands-on sessions. Class topics ranged from statistical data analysis and machine learning to brain-computer interfaces, brain imaging, signal processing of neural activity data, and cryogenic electron microscopy.

      “This workshop could not happen without dedicated instructors — grad students, postdocs, and faculty — who volunteer to give lectures, design and teach hands-on computer labs, and meet with students during the very first week of January,” Saassanfar says.

      MIT assistant professor of biology Brady Weissbourd (center) converses with QMW student participants during a lunch break.

      Photo: Mandana Sassanfar

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      The sessions surround student lunches with MIT faculty members. For example, at midday Jan. 2, assistant professor of biology Brady Weissbourd, an investigator in the Picower Institute, sat down with seven students in one of Building 46’s curved sofas to field questions about his neuroscience research in jellyfish and how he uses quantitative techniques as part of that work. He also described what it’s like to be a professor, and other topics that came to the students’ minds.

      Then the participants all crossed Vassar Street to Building 26’s Room 152, where they formed different but similarly sized groups for the hands-on lab “Machine learning applications to studying the brain,” taught by Baum. She guided the class through Python exercises she developed illustrating “supervised” and “unsupervised” forms of machine learning, including how the latter method can be used to discern what a person is seeing based on magnetic readings of brain activity.

      As students worked through the exercises, tablemates helped each other by supplementing Baum’s instruction. Ligorio, Vostrikov, and Kayla Blincow, assistant professor of biology at the University of the Virgin Islands, for instance, all leapt to their feet to help at their tables.

      Hunter College lecturer of computer science Tiziana Ligorio (standing) explains a Python programming concept to students at her table during a workshop session.

      Photo: David Orenstein

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      At the end of the class, when Baum asked students what they had learned, they offered a litany of new knowledge. Survey data that Sassanfar and Sánchez-Jáuregui use to anonymously track QMW outcomes, revealed many more such attestations of the value of the sessions. With a prompt asking how one might apply what they’ve learned, one respondent wrote: “Pursue a research career or endeavor in which I apply the concepts of computer science and neuroscience together.”

      Enduring connections

      While some new QMW attendees might only be able to speculate about how they’ll apply their new skills and relationships, Luis Miguel de Jesús Astacio could testify to how attending QMW as an undergraduate back in 2014 figured into a career where he is now a faculty member in physics at the University of Puerto Rico Rio Piedras Campus. After QMW, he returned to MIT that summer as a student in the lab of neuroscientist and Picower Professor Susumu Tonegawa. He came back again in 2016 to the lab of physicist and Francis Friedman Professor Mehran Kardar. What’s endured for the decade has been his connection to Sassanfar. So while he was once a student at QMW, this year he was back with a cohort of undergraduates as a faculty member.

      Michael Aldarondo-Jeffries, director of academic advancement programs at the University of Central Florida, seconded the value of the networking that takes place at QMW. He has brought students for a decade, including four this year. What he’s observed is that as students come together in settings like QMW or UCF’s McNair program, which helps to prepare students for graduate school, they become inspired about a potential future as researchers.

      “The thing that stands out is just the community that’s formed,” he says. “For many of the students, it’s the first time that they’re in a group that understands what they’re moving toward. They don’t have to explain why they’re excited to read papers on a Friday night.”

      Or why they are excited to spend a week including New Year’s Day at MIT learning how to apply quantitative methods to life sciences data. More

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      Generating the policy of tomorrow

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      As first-year students in the Social and Engineering Systems (SES) doctoral program within the MIT Institute for Data, Systems, and Society (IDSS), Eric Liu and Ashely Peake share an interest in investigating housing inequality issues.

      They also share a desire to dive head-first into their research.

      “In the first year of your PhD, you’re taking classes and still getting adjusted, but we came in very eager to start doing research,” Liu says.

      Liu, Peake, and many others found an opportunity to do hands-on research on real-world problems at the MIT Policy Hackathon, an initiative organized by students in IDSS, including the Technology and Policy Program (TPP). The weekend-long, interdisciplinary event — now in its sixth year — continues to gather hundreds of participants from around the globe to explore potential solutions to some of society’s greatest challenges.

      This year’s theme, “Hack-GPT: Generating the Policy of Tomorrow,” sought to capitalize on the popularity of generative AI (like the chatbot ChatGPT) and the ways it is changing how we think about technical and policy-based challenges, according to Dansil Green, a second-year TPP master’s student and co-chair of the event.

      “We encouraged our teams to utilize and cite these tools, thinking about the implications that generative AI tools have on their different challenge categories,” Green says.

      After 2022’s hybrid event, this year’s organizers pivoted back to a virtual-only approach, allowing them to increase the overall number of participants in addition to increasing the number of teams per challenge by 20 percent.

      “Virtual allows you to reach more people — we had a high number of international participants this year — and it helps reduce some of the costs,” Green says. “I think going forward we are going to try and switch back and forth between virtual and in-person because there are different benefits to each.”

      “When the magic hits”

      Liu and Peake competed in the housing challenge category, where they could gain research experience in their actual field of study. 

      “While I am doing housing research, I haven’t necessarily had a lot of opportunities to work with actual housing data before,” says Peake, who recently joined the SES doctoral program after completing an undergraduate degree in applied math last year. “It was a really good experience to get involved with an actual data problem, working closer with Eric, who’s also in my lab group, in addition to meeting people from MIT and around the world who are interested in tackling similar questions and seeing how they think about things differently.”

      Joined by Adrian Butterton, a Boston-based paralegal, as well as Hudson Yuen and Ian Chan, two software engineers from Canada, Liu and Peake formed what would end up being the winning team in their category: “Team Ctrl+Alt+Defeat.” They quickly began organizing a plan to address the eviction crisis in the United States.

      “I think we were kind of surprised by the scope of the question,” Peake laughs. “In the end, I think having such a large scope motivated us to think about it in a more realistic kind of way — how could we come up with a solution that was adaptable and therefore could be replicated to tackle different kinds of problems.”

      Watching the challenge on the livestream together on campus, Liu says they immediately went to work, and could not believe how quickly things came together.

      “We got our challenge description in the evening, came out to the purple common area in the IDSS building and literally it took maybe an hour and we drafted up the entire project from start to finish,” Liu says. “Then our software engineer partners had a dashboard built by 1 a.m. — I feel like the hackathon really promotes that really fast dynamic work stream.”

      “People always talk about the grind or applying for funding — but when that magic hits, it just reminds you of the part of research that people don’t talk about, and it was really a great experience to have,” Liu adds.

      A fresh perspective

      “We’ve organized hackathons internally at our company and they are great for fostering innovation and creativity,” says Letizia Bordoli, senior AI product manager at Veridos, a German-based identity solutions company that provided this year’s challenge in Data Systems for Human Rights. “It is a great opportunity to connect with talented individuals and explore new ideas and solutions that we might not have thought about.”

      The challenge provided by Veridos was focused on finding innovative solutions to universal birth registration, something Bordoli says only benefited from the fact that the hackathon participants were from all over the world.

      “Many had local and firsthand knowledge about certain realities and challenges [posed by the lack of] birth registration,” Bordoli says. “It brings fresh perspectives to existing challenges, and it gave us an energy boost to try to bring innovative solutions that we may not have considered before.”

      New frontiers

      Alongside the housing and data systems for human rights challenges was a challenge in health, as well as a first-time opportunity to tackle an aerospace challenge in the area of space for environmental justice.

      “Space can be a very hard challenge category to do data-wise since a lot of data is proprietary, so this really developed over the last few months with us having to think about how we could do more with open-source data,” Green explains. “But I am glad we went the environmental route because it opened the challenge up to not only space enthusiasts, but also environment and climate people.”

      One of the participants to tackle this new challenge category was Yassine Elhallaoui, a system test engineer from Norway who specializes in AI solutions and has 16 years of experience working in the oil and gas fields. Elhallaoui was a member of Team EcoEquity, which proposed an increase in policies supporting the use of satellite data to ensure proper evaluation and increase water resiliency for vulnerable communities.

      “The hackathons I have participated in in the past were more technical,” Elhallaoui says. “Starting with [MIT Science and Technology Policy Institute Director Kristen Kulinowski’s] workshop about policy writers and the solutions they came up with, and the analysis they had to do … it really changed my perspective on what a hackathon can do.”

      “A policy hackathon is something that can make real changes in the world,” she adds. More

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      Inclusive research for social change

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      Pair a decades-old program dedicated to creating research opportunities for underrepresented minorities and populations with a growing initiative committed to tackling the very issues at the heart of such disparities, and you’ll get a transformative partnership that only MIT can deliver. 

      Since 1986, the MIT Summer Research Program (MSRP) has led an institutional effort to prepare underrepresented students (minorities, women in STEM, or students with low socioeconomic status) for doctoral education by pairing them with MIT labs and research groups. For the past three years, the Initiative on Combatting Systemic Racism (ICSR), a cross-disciplinary research collaboration led by MIT’s Institute for Data, Systems, and Society (IDSS), has joined them in their mission, helping bring the issue full circle by providing MSRP students with the opportunity to use big data and computational tools to create impactful changes toward racial equity.

      “ICSR has further enabled our direct engagement with undergrads, both within and outside of MIT,” says Fotini Christia, the Ford International Professor of the Social Sciences, associate director of IDSS, and co-organizer for the initiative. “We’ve found that this line of research has attracted students interested in examining these topics with the most rigorous methods.”

      The initiative fits well under the IDSS banner, as IDSS research seeks solutions to complex societal issues through a multidisciplinary approach that includes statistics, computation, modeling, social science methodologies, human behavior, and an understanding of complex systems. With the support of faculty and researchers from all five schools and the MIT Schwarzman College of Computing, the objective of ICSR is to work on an array of different societal aspects of systemic racism through a set of verticals including policing, housing, health care, and social media.

      Where passion meets impact

      Grinnell senior Mia Hines has always dreamed of using her love for computer science to support social justice. She has experience working with unhoused people and labor unions, and advocating for Indigenous peoples’ rights. When applying to college, she focused her essay on using technology to help Syrian refugees.

      “As a Black woman, it’s very important to me that we focus on these areas, especially on how we can use technology to help marginalized communities,” Hines says. “And also, how do we stop technology or improve technology that is already hurting marginalized communities?”   

      Through MSRP, Hines was paired with research advisor Ufuoma Ovienmhada, a fourth-year doctoral student in the Department of Aeronautics and Astronautics at MIT. A member of Professor Danielle Wood’s Space Enabled research group at MIT’s Media Lab, Ovienmhada received funding from an ICSR Seed Grant and NASA’s Applied Sciences Program to support her ongoing research measuring environmental injustice and socioeconomic disparities in prison landscapes. 

      “I had been doing satellite remote sensing for environmental challenges and sustainability, starting out looking at coastal ecosystems, when I learned about an issue called ‘prison ecology,’” Ovienmhada explains. “This refers to the intersection of mass incarceration and environmental justice.”

      Ovienmhada’s research uses satellite remote sensing and environmental data to characterize exposures to different environmental hazards such as air pollution, extreme heat, and flooding. “This allows others to use these datasets for real-time advocacy, in addition to creating public awareness,” she says.

      Focused especially on extreme heat, Hines used satellite remote sensing to monitor the fluctuation of temperature to assess the risk being imposed on prisoners, including death, especially in states like Texas, where 75 percent of prisons either don’t have full air conditioning or have none at all.

      “Before this project I had done little to no work with geospatial data, and as a budding data scientist, getting to work with and understanding different types of data and resources is really helpful,” Hines says. “I was also funded and afforded the flexibility to take advantage of IDSS’s Data Science and Machine Learning online course. It was really great to be able to do that and learn even more.”

      Filling the gap

      Much like Hines, Harvey Mudd senior Megan Li was specifically interested in the IDSS-supported MSRP projects. She was drawn to the interdisciplinary approach, and she seeks in her own work to apply computational methods to societal issues and to make computer science more inclusive, considerate, and ethical. 

      Working with Aurora Zhang, a grad student in IDSS’s Social and Engineering Systems PhD program, Li used county-level data on income and housing prices to quantify and visualize how affordability based on income alone varies across the United States. She then expanded the analysis to include assets and debt to determine the most common barriers to home ownership.

      “I spent my day-to-day looking at census data and writing Python scripts that could work with it,” reports Li. “I also reached out to the Census Bureau directly to learn a little bit more about how they did their data collection, and discussed questions related to some of their previous studies and working papers that I had reviewed.” 

      Outside of actual day-to-day research, Li says she learned a lot in conversations with fellow researchers, particularly changing her “skeptical view” of whether or not mortgage lending algorithms would help or hurt home buyers in the approval process. “I think I have a little bit more faith now, which is a good thing.”

      “Harvey Mudd is undergraduate-only, and while professors do run labs here, my specific research areas are not well represented,” Li says. “This opportunity was enormous in that I got the experience I need to see if this research area is actually something that I want to do long term, and I got more mirrors into what I would be doing in grad school from talking to students and getting to know faculty.”

      Closing the loop

      While participating in MSRP offered crucial research experience to Hines, the ICSR projects enabled her to engage in topics she’s passionate about and work that could drive tangible societal change.

      “The experience felt much more concrete because we were working on these very sophisticated projects, in a supportive environment where people were very excited to work with us,” she says.

      A significant benefit for Li was the chance to steer her research in alignment with her own interests. “I was actually given the opportunity to propose my own research idea, versus supporting a graduate student’s work in progress,” she explains. 

      For Ovienmhada, the pairing of the two initiatives solidifies the efforts of MSRP and closes a crucial loop in diversity, equity, and inclusion advocacy. 

      “I’ve participated in a lot of different DEI-related efforts and advocacy and one thing that always comes up is the fact that it’s not just about bringing people in, it’s also about creating an environment and opportunities that align with people’s values,” Ovienmhada says. “Programs like MSRP and ICSR create opportunities for people who want to do work that’s aligned with certain values by providing the needed mentoring and financial support.” More

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      Leveraging language to understand machines

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      Natural language conveys ideas, actions, information, and intent through context and syntax; further, there are volumes of it contained in databases. This makes it an excellent source of data to train machine-learning systems on. Two master’s of engineering students in the 6A MEng Thesis Program at MIT, Irene Terpstra ’23 and Rujul Gandhi ’22, are working with mentors in the MIT-IBM Watson AI Lab to use this power of natural language to build AI systems.

      As computing is becoming more advanced, researchers are looking to improve the hardware that they run on; this means innovating to create new computer chips. And, since there is literature already available on modifications that can be made to achieve certain parameters and performance, Terpstra and her mentors and advisors Anantha Chandrakasan, MIT School of Engineering dean and the Vannevar Bush Professor of Electrical Engineering and Computer Science, and IBM’s researcher Xin Zhang, are developing an AI algorithm that assists in chip design.

      “I’m creating a workflow to systematically analyze how these language models can help the circuit design process. What reasoning powers do they have, and how can it be integrated into the chip design process?” says Terpstra. “And then on the other side, if that proves to be useful enough, [we’ll] see if they can automatically design the chips themselves, attaching it to a reinforcement learning algorithm.”

      To do this, Terpstra’s team is creating an AI system that can iterate on different designs. It means experimenting with various pre-trained large language models (like ChatGPT, Llama 2, and Bard), using an open-source circuit simulator language called NGspice, which has the parameters of the chip in code form, and a reinforcement learning algorithm. With text prompts, researchers will be able to query how the physical chip should be modified to achieve a certain goal in the language model and produced guidance for adjustments. This is then transferred into a reinforcement learning algorithm that updates the circuit design and outputs new physical parameters of the chip.

      “The final goal would be to combine the reasoning powers and the knowledge base that is baked into these large language models and combine that with the optimization power of the reinforcement learning algorithms and have that design the chip itself,” says Terpstra.

      Rujul Gandhi works with the raw language itself. As an undergraduate at MIT, Gandhi explored linguistics and computer sciences, putting them together in her MEng work. “I’ve been interested in communication, both between just humans and between humans and computers,” Gandhi says.

      Robots or other interactive AI systems are one area where communication needs to be understood by both humans and machines. Researchers often write instructions for robots using formal logic. This helps ensure that commands are being followed safely and as intended, but formal logic can be difficult for users to understand, while natural language comes easily. To ensure this smooth communication, Gandhi and her advisors Yang Zhang of IBM and MIT assistant professor Chuchu Fan are building a parser that converts natural language instructions into a machine-friendly form. Leveraging the linguistic structure encoded by the pre-trained encoder-decoder model T5, and a dataset of annotated, basic English commands for performing certain tasks, Gandhi’s system identifies the smallest logical units, or atomic propositions, which are present in a given instruction.

      “Once you’ve given your instruction, the model identifies all the smaller sub-tasks you want it to carry out,” Gandhi says. “Then, using a large language model, each sub-task can be compared against the available actions and objects in the robot’s world, and if any sub-task can’t be carried out because a certain object is not recognized, or an action is not possible, the system can stop right there to ask the user for help.”

      This approach of breaking instructions into sub-tasks also allows her system to understand logical dependencies expressed in English, like, “do task X until event Y happens.” Gandhi uses a dataset of step-by-step instructions across robot task domains like navigation and manipulation, with a focus on household tasks. Using data that are written just the way humans would talk to each other has many advantages, she says, because it means a user can be more flexible about how they phrase their instructions.

      Another of Gandhi’s projects involves developing speech models. In the context of speech recognition, some languages are considered “low resource” since they might not have a lot of transcribed speech available, or might not have a written form at all. “One of the reasons I applied to this internship at the MIT-IBM Watson AI Lab was an interest in language processing for low-resource languages,” she says. “A lot of language models today are very data-driven, and when it’s not that easy to acquire all of that data, that’s when you need to use the limited data efficiently.” 

      Speech is just a stream of sound waves, but humans having a conversation can easily figure out where words and thoughts start and end. In speech processing, both humans and language models use their existing vocabulary to recognize word boundaries and understand the meaning. In low- or no-resource languages, a written vocabulary might not exist at all, so researchers can’t provide one to the model. Instead, the model can make note of what sound sequences occur together more frequently than others, and infer that those might be individual words or concepts. In Gandhi’s research group, these inferred words are then collected into a pseudo-vocabulary that serves as a labeling method for the low-resource language, creating labeled data for further applications.

      The applications for language technology are “pretty much everywhere,” Gandhi says. “You could imagine people being able to interact with software and devices in their native language, their native dialect. You could imagine improving all the voice assistants that we use. You could imagine it being used for translation or interpretation.” More

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      Three MIT students selected as inaugural MIT-Pillar AI Collective Fellows

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      MIT-Pillar AI Collective has announced three inaugural fellows for the fall 2023 semester. With support from the program, the graduate students, who are in their final year of a master’s or PhD program, will conduct research in the areas of artificial intelligence, machine learning, and data science with the aim of commercializing their innovations.

      Launched by MIT’s School of Engineering and Pillar VC in 2022, the MIT-Pillar AI Collective supports faculty, postdocs, and students conducting research on AI, machine learning, and data science. Supported by a gift from Pillar VC and administered by the MIT Deshpande Center for Technological Innovation, the mission of the program is to advance research toward commercialization.

      The fall 2023 MIT-Pillar AI Collective Fellows are:

      Alexander Andonian SM ’21 is a PhD candidate in electrical engineering and computer science whose research interests lie in computer vision, deep learning, and artificial intelligence. More specifically, he is focused on building a generalist, multimodal AI scientist driven by generative vision-language model agents capable of proposing scientific hypotheses, running computational experiments, evaluating supporting evidence, and verifying conclusions in the same way as a human researcher or reviewer. Such an agent could be trained to optimally distill and communicate its findings for human consumption and comprehension. Andonian’s work holds the promise of creating a concrete foundation for rigorously building and holistically testing the next-generation autonomous AI agent for science. In addition to his research, Andonian is the CEO and co-founder of Reelize, a startup that offers a generative AI video tool that effortlessly turns long videos into short clips — and originated from his business coursework and was supported by MIT Sandbox. Andonian is also a founding AI researcher at Poly AI, an early-stage YC-backed startup building AI design tools. Andonian earned an SM from MIT and a BS in neuroscience, physics, and mathematics from Bates College.

      Daniel Magley is a PhD candidate in the Harvard-MIT Program in Health Sciences and Technology who is passionate about making a healthy, fully functioning mind and body a reality for all. His leading-edge research is focused on developing a swallowable wireless thermal imaging capsule that could be used in treating and monitoring inflammatory bowel diseases and their manifestations, such as Crohn’s disease. Providing increased sensitivity and eliminating the need for bowel preparation, the capsule has the potential to vastly improve treatment efficacy and overall patient experience in routine monitoring. The capsule has completed animal studies and is entering human studies at Mass General Brigham, where Magley leads a team of engineers in the hospital’s largest translational research lab, the Tearney Lab. Following the human pilot studies, the largest technological and regulatory risks will be cleared for translation. Magley will then begin focusing on a multi-site study to get the device into clinics, with the promise of benefiting patients across the country. Magley earned a BS in electrical engineering from Caltech.

      Madhumitha Ravichandra is a PhD candidate interested in advancing heat transfer and surface engineering techniques to enhance the safety and performance of nuclear energy systems and reduce their environmental impacts. Leveraging her deep knowledge of the integration of explainable AI with high-throughput autonomous experimentation, she seeks to transform the development of radiation-hardened (rad-hard) sensors, which could potentially withstand and function amidst radiation levels that would render conventional sensors useless. By integrating explainable AI with high-throughput autonomous experimentation, she aims to rapidly iterate designs, test under varied conditions, and ensure that the final product is both robust and transparent in its operations. Her work in this space could shift the paradigm in rad-hard sensor development, addressing a glaring void in the market and redefining standards, ensuring that nuclear and space applications are safer, more efficient, and at the cutting edge of technological progress. Ravichandran earned a BTech in mechanical engineering from SASTRA University, India. More