More stories

  • in

    Growing our donated organ supply

    For those in need of one, an organ transplant is a matter of life and death. 

    Every year, the medical procedure gives thousands of people with advanced or end-stage diseases extended life. This “second chance” is heavily dependent on the availability, compatibility, and proximity of a precious resource that can’t be simply bought, grown, or manufactured — at least not yet.

    Instead, organs must be given — cut from one body and implanted into another. And because living organ donation is only viable in certain cases, many organs are only available for donation after the donor’s death.

    Unsurprisingly, the logistical and ethical complexity of distributing a limited number of transplant organs to a growing wait list of patients has received much attention. There’s an important part of the process that has received less focus, however, and which may hold significant untapped potential: organ procurement itself.

    “If you have a donated organ, who should you give it to? This question has been extensively studied in operations research, economics, and even applied computer science,” says Hammaad Adam, a graduate student in the Social and Engineering Systems (SES) doctoral program at the MIT Institute for Data, Systems, and Society (IDSS). “But there’s been a lot less research on where that organ comes from in the first place.”

    In the United States, nonprofits called organ procurement organizations, or OPOs, are responsible for finding and evaluating potential donors, interacting with grieving families and hospital administrations, and recovering and delivering organs — all while following the federal laws that serve as both their mandate and guardrails. Recent studies estimate that obstacles and inefficiencies lead to thousands of organs going uncollected every year, even as the demand for transplants continues to grow.

    “There’s been little transparent data on organ procurement,” argues Adam. Working with MIT computer science professors Marzyeh Ghassemi and Ashia Wilson, and in collaboration with stakeholders in organ procurement, Adam led a project to create a dataset called ORCHID: Organ Retrieval and Collection of Health Information for Donation. ORCHID contains a decade of clinical, financial, and administrative data from six OPOs.

    “Our goal is for the ORCHID database to have an impact in how organ procurement is understood, internally and externally,” says Ghassemi.

    Efficiency and equity 

    It was looking to make an impact that drew Adam to SES and MIT. With a background in applied math and experience in strategy consulting, solving problems with technical components sits right in his wheelhouse.

    “I really missed challenging technical problems from a statistics and machine learning standpoint,” he says of his time in consulting. “So I went back and got a master’s in data science, and over the course of my master’s got involved in a bunch of academic research projects in a few different fields, including biology, management science, and public policy. What I enjoyed most were some of the more social science-focused projects that had immediate impact.”

    As a grad student in SES, Adam’s research focuses on using statistical tools to uncover health-care inequities, and developing machine learning approaches to address them. “Part of my dissertation research focuses on building tools that can improve equity in clinical trials and other randomized experiments,” he explains.

    One recent example of Adam’s work: developing a novel method to stop clinical trials early if the treatment has an unintended harmful effect for a minority group of participants. “I’ve also been thinking about ways to increase minority representation in clinical trials through improved patient recruitment,” he adds.

    Racial inequities in health care extend into organ transplantation, where a majority of wait-listed patients are not white — far in excess of their demographic groups’ proportion to the overall population. There are fewer organ donations from many of these communities, due to various obstacles in need of better understanding if they are to be overcome. 

    “My work in organ transplantation began on the allocation side,” explains Adam. “In work under review, we examined the role of race in the acceptance of heart, liver, and lung transplant offers by physicians on behalf of their patients. We found that Black race of the patient was associated with significantly lower odds of organ offer acceptance — in other words, transplant doctors seemed more likely to turn down organs offered to Black patients. This trend may have multiple explanations, but it is nevertheless concerning.”

    Adam’s research has also found that donor-candidate race match was associated with significantly higher odds of offer acceptance, an association that Adam says “highlights the importance of organ donation from racial minority communities, and has motivated our work on equitable organ procurement.”

    Working with Ghassemi through the IDSS Initiative on Combatting Systemic Racism, Adam was introduced to OPO stakeholders looking to collaborate. “It’s this opportunity to impact not only health-care efficiency, but also health-care equity, that really got me interested in this research,” says Adam.

    Play video

    MIT Initiative on Combatting Systemic Racism – HealthcareVideo: IDSS

    Making an impact

    Creating a database like ORCHID means solving problems in multiple domains, from the technical to the political. Some efforts never overcome the first step: getting data in the first place. Thankfully, several OPOs were already seeking collaborations and looking to improve their performance.

    “We have been lucky to have a strong partnership with the OPOs, and we hope to work together to find important insights to improve efficiency and equity,” says Ghassemi.

    The value of a database like ORCHID is in its potential for generating new insights, especially through quantitative analysis with statistics and computing tools like machine learning. The potential value in ORCHID was recognized with an MIT Prize for Open Data, an MIT Libraries award highlighting the importance and impact of research data that is openly shared.

    “It’s nice that the work got some recognition,” says Adam of the prize. “And it was cool to see some of the other great open data work that’s happening at MIT. I think there’s real impact in releasing publicly available data in an important and understudied domain.”

    All the same, Adam knows that building the database is only the first step.

    “I’m very interested in understanding the bottlenecks in the organ procurement process,” he explains. “As part of my thesis research, I’m exploring this by modeling OPO decision-making using causal inference and structural econometrics.”

    Using insights from this research, Adam also aims to evaluate policy changes that can improve both equity and efficiency in organ procurement. “And we’re hoping to recruit more OPOs, and increase the amount of data we’re releasing,” he says. “The dream state is every OPO joins our collaboration and provides updated data every year.”

    Adam is excited to see how other researchers might use the data to address inefficiencies in organ procurement. “Every organ donor saves between three and four lives,” he says. “So every research project that comes out of this dataset could make a real impact.” More

  • in

    New software enables blind and low-vision users to create interactive, accessible charts

    A growing number of tools enable users to make online data representations, like charts, that are accessible for people who are blind or have low vision. However, most tools require an existing visual chart that can then be converted into an accessible format.

    This creates barriers that prevent blind and low-vision users from building their own custom data representations, and it can limit their ability to explore and analyze important information.

    A team of researchers from MIT and University College London (UCL) wants to change the way people think about accessible data representations.

    They created a software system called Umwelt (which means “environment” in German) that can enable blind and low-vision users to build customized, multimodal data representations without needing an initial visual chart.

    Umwelt, an authoring environment designed for screen-reader users, incorporates an editor that allows someone to upload a dataset and create a customized representation, such as a scatterplot, that can include three modalities: visualization, textual description, and sonification. Sonification involves converting data into nonspeech audio.

    The system, which can represent a variety of data types, includes a viewer that enables a blind or low-vision user to interactively explore a data representation, seamlessly switching between each modality to interact with data in a different way.

    The researchers conducted a study with five expert screen-reader users who found Umwelt to be useful and easy to learn. In addition to offering an interface that empowered them to create data representations — something they said was sorely lacking — the users said Umwelt could facilitate communication between people who rely on different senses.

    “We have to remember that blind and low-vision people aren’t isolated. They exist in these contexts where they want to talk to other people about data,” says Jonathan Zong, an electrical engineering and computer science (EECS) graduate student and lead author of a paper introducing Umwelt. “I am hopeful that Umwelt helps shift the way that researchers think about accessible data analysis. Enabling the full participation of blind and low-vision people in data analysis involves seeing visualization as just one piece of this bigger, multisensory puzzle.”

    Joining Zong on the paper are fellow EECS graduate students Isabella Pedraza Pineros and Mengzhu “Katie” Chen; Daniel Hajas, a UCL researcher who works with the Global Disability Innovation Hub; and senior author Arvind Satyanarayan, associate professor of computer science at MIT who leads the Visualization Group in the Computer Science and Artificial Intelligence Laboratory. The paper will be presented at the ACM Conference on Human Factors in Computing.

    De-centering visualization

    The researchers previously developed interactive interfaces that provide a richer experience for screen reader users as they explore accessible data representations. Through that work, they realized most tools for creating such representations involve converting existing visual charts.

    Aiming to decenter visual representations in data analysis, Zong and Hajas, who lost his sight at age 16, began co-designing Umwelt more than a year ago.

    At the outset, they realized they would need to rethink how to represent the same data using visual, auditory, and textual forms.

    “We had to put a common denominator behind the three modalities. By creating this new language for representations, and making the output and input accessible, the whole is greater than the sum of its parts,” says Hajas.

    To build Umwelt, they first considered what is unique about the way people use each sense.

    For instance, a sighted user can see the overall pattern of a scatterplot and, at the same time, move their eyes to focus on different data points. But for someone listening to a sonification, the experience is linear since data are converted into tones that must be played back one at a time.

    “If you are only thinking about directly translating visual features into nonvisual features, then you miss out on the unique strengths and weaknesses of each modality,” Zong adds.

    They designed Umwelt to offer flexibility, enabling a user to switch between modalities easily when one would better suit their task at a given time.

    To use the editor, one uploads a dataset to Umwelt, which employs heuristics to automatically creates default representations in each modality.

    If the dataset contains stock prices for companies, Umwelt might generate a multiseries line chart, a textual structure that groups data by ticker symbol and date, and a sonification that uses tone length to represent the price for each date, arranged by ticker symbol.

    The default heuristics are intended to help the user get started.

    “In any kind of creative tool, you have a blank-slate effect where it is hard to know how to begin. That is compounded in a multimodal tool because you have to specify things in three different representations,” Zong says.

    The editor links interactions across modalities, so if a user changes the textual description, that information is adjusted in the corresponding sonification. Someone could utilize the editor to build a multimodal representation, switch to the viewer for an initial exploration, then return to the editor to make adjustments.

    Helping users communicate about data

    To test Umwelt, they created a diverse set of multimodal representations, from scatterplots to multiview charts, to ensure the system could effectively represent different data types. Then they put the tool in the hands of five expert screen reader users.

    Study participants mostly found Umwelt to be useful for creating, exploring, and discussing data representations. One user said Umwelt was like an “enabler” that decreased the time it took them to analyze data. The users agreed that Umwelt could help them communicate about data more easily with sighted colleagues.

    “What stands out about Umwelt is its core philosophy of de-emphasizing the visual in favor of a balanced, multisensory data experience. Often, nonvisual data representations are relegated to the status of secondary considerations, mere add-ons to their visual counterparts. However, visualization is merely one aspect of data representation. I appreciate their efforts in shifting this perception and embracing a more inclusive approach to data science,” says JooYoung Seo, an assistant professor in the School of Information Sciences at the University of Illinois at Urbana-Champagne, who was not involved with this work.

    Moving forward, the researchers plan to create an open-source version of Umwelt that others can build upon. They also want to integrate tactile sensing into the software system as an additional modality, enabling the use of tools like refreshable tactile graphics displays.

    “In addition to its impact on end users, I am hoping that Umwelt can be a platform for asking scientific questions around how people use and perceive multimodal representations, and how we can improve the design beyond this initial step,” says Zong.

    This work was supported, in part, by the National Science Foundation and the MIT Morningside Academy for Design Fellowship. More

  • in

    AI generates high-quality images 30 times faster in a single step

    In our current age of artificial intelligence, computers can generate their own “art” by way of diffusion models, iteratively adding structure to a noisy initial state until a clear image or video emerges. Diffusion models have suddenly grabbed a seat at everyone’s table: Enter a few words and experience instantaneous, dopamine-spiking dreamscapes at the intersection of reality and fantasy. Behind the scenes, it involves a complex, time-intensive process requiring numerous iterations for the algorithm to perfect the image.

    MIT Computer Science and Artificial Intelligence Laboratory (CSAIL) researchers have introduced a new framework that simplifies the multi-step process of traditional diffusion models into a single step, addressing previous limitations. This is done through a type of teacher-student model: teaching a new computer model to mimic the behavior of more complicated, original models that generate images. The approach, known as distribution matching distillation (DMD), retains the quality of the generated images and allows for much faster generation. 

    “Our work is a novel method that accelerates current diffusion models such as Stable Diffusion and DALLE-3 by 30 times,” says Tianwei Yin, an MIT PhD student in electrical engineering and computer science, CSAIL affiliate, and the lead researcher on the DMD framework. “This advancement not only significantly reduces computational time but also retains, if not surpasses, the quality of the generated visual content. Theoretically, the approach marries the principles of generative adversarial networks (GANs) with those of diffusion models, achieving visual content generation in a single step — a stark contrast to the hundred steps of iterative refinement required by current diffusion models. It could potentially be a new generative modeling method that excels in speed and quality.”

    This single-step diffusion model could enhance design tools, enabling quicker content creation and potentially supporting advancements in drug discovery and 3D modeling, where promptness and efficacy are key.

    Distribution dreams

    DMD cleverly has two components. First, it uses a regression loss, which anchors the mapping to ensure a coarse organization of the space of images to make training more stable. Next, it uses a distribution matching loss, which ensures that the probability to generate a given image with the student model corresponds to its real-world occurrence frequency. To do this, it leverages two diffusion models that act as guides, helping the system understand the difference between real and generated images and making training the speedy one-step generator possible.

    The system achieves faster generation by training a new network to minimize the distribution divergence between its generated images and those from the training dataset used by traditional diffusion models. “Our key insight is to approximate gradients that guide the improvement of the new model using two diffusion models,” says Yin. “In this way, we distill the knowledge of the original, more complex model into the simpler, faster one, while bypassing the notorious instability and mode collapse issues in GANs.” 

    Yin and colleagues used pre-trained networks for the new student model, simplifying the process. By copying and fine-tuning parameters from the original models, the team achieved fast training convergence of the new model, which is capable of producing high-quality images with the same architectural foundation. “This enables combining with other system optimizations based on the original architecture to further accelerate the creation process,” adds Yin. 

    When put to the test against the usual methods, using a wide range of benchmarks, DMD showed consistent performance. On the popular benchmark of generating images based on specific classes on ImageNet, DMD is the first one-step diffusion technique that churns out pictures pretty much on par with those from the original, more complex models, rocking a super-close Fréchet inception distance (FID) score of just 0.3, which is impressive, since FID is all about judging the quality and diversity of generated images. Furthermore, DMD excels in industrial-scale text-to-image generation and achieves state-of-the-art one-step generation performance. There’s still a slight quality gap when tackling trickier text-to-image applications, suggesting there’s a bit of room for improvement down the line. 

    Additionally, the performance of the DMD-generated images is intrinsically linked to the capabilities of the teacher model used during the distillation process. In the current form, which uses Stable Diffusion v1.5 as the teacher model, the student inherits limitations such as rendering detailed depictions of text and small faces, suggesting that DMD-generated images could be further enhanced by more advanced teacher models. 

    “Decreasing the number of iterations has been the Holy Grail in diffusion models since their inception,” says Fredo Durand, MIT professor of electrical engineering and computer science, CSAIL principal investigator, and a lead author on the paper. “We are very excited to finally enable single-step image generation, which will dramatically reduce compute costs and accelerate the process.” 

    “Finally, a paper that successfully combines the versatility and high visual quality of diffusion models with the real-time performance of GANs,” says Alexei Efros, a professor of electrical engineering and computer science at the University of California at Berkeley who was not involved in this study. “I expect this work to open up fantastic possibilities for high-quality real-time visual editing.” 

    Yin and Durand’s fellow authors are MIT electrical engineering and computer science professor and CSAIL principal investigator William T. Freeman, as well as Adobe research scientists Michaël Gharbi SM ’15, PhD ’18; Richard Zhang; Eli Shechtman; and Taesung Park. Their work was supported, in part, by U.S. National Science Foundation grants (including one for the Institute for Artificial Intelligence and Fundamental Interactions), the Singapore Defense Science and Technology Agency, and by funding from Gwangju Institute of Science and Technology and Amazon. Their work will be presented at the Conference on Computer Vision and Pattern Recognition in June. More

  • in

    Dealing with the limitations of our noisy world

    Tamara Broderick first set foot on MIT’s campus when she was a high school student, as a participant in the inaugural Women’s Technology Program. The monthlong summer academic experience gives young women a hands-on introduction to engineering and computer science.

    What is the probability that she would return to MIT years later, this time as a faculty member?

    That’s a question Broderick could probably answer quantitatively using Bayesian inference, a statistical approach to probability that tries to quantify uncertainty by continuously updating one’s assumptions as new data are obtained.

    In her lab at MIT, the newly tenured associate professor in the Department of Electrical Engineering and Computer Science (EECS) uses Bayesian inference to quantify uncertainty and measure the robustness of data analysis techniques.

    “I’ve always been really interested in understanding not just ‘What do we know from data analysis,’ but ‘How well do we know it?’” says Broderick, who is also a member of the Laboratory for Information and Decision Systems and the Institute for Data, Systems, and Society. “The reality is that we live in a noisy world, and we can’t always get exactly the data that we want. How do we learn from data but at the same time recognize that there are limitations and deal appropriately with them?”

    Broadly, her focus is on helping people understand the confines of the statistical tools available to them and, sometimes, working with them to craft better tools for a particular situation.

    For instance, her group recently collaborated with oceanographers to develop a machine-learning model that can make more accurate predictions about ocean currents. In another project, she and others worked with degenerative disease specialists on a tool that helps severely motor-impaired individuals utilize a computer’s graphical user interface by manipulating a single switch.

    A common thread woven through her work is an emphasis on collaboration.

    “Working in data analysis, you get to hang out in everybody’s backyard, so to speak. You really can’t get bored because you can always be learning about some other field and thinking about how we can apply machine learning there,” she says.

    Hanging out in many academic “backyards” is especially appealing to Broderick, who struggled even from a young age to narrow down her interests.

    A math mindset

    Growing up in a suburb of Cleveland, Ohio, Broderick had an interest in math for as long as she can remember. She recalls being fascinated by the idea of what would happen if you kept adding a number to itself, starting with 1+1=2 and then 2+2=4.

    “I was maybe 5 years old, so I didn’t know what ‘powers of two’ were or anything like that. I was just really into math,” she says.

    Her father recognized her interest in the subject and enrolled her in a Johns Hopkins program called the Center for Talented Youth, which gave Broderick the opportunity to take three-week summer classes on a range of subjects, from astronomy to number theory to computer science.

    Later, in high school, she conducted astrophysics research with a postdoc at Case Western University. In the summer of 2002, she spent four weeks at MIT as a member of the first class of the Women’s Technology Program.

    She especially enjoyed the freedom offered by the program, and its focus on using intuition and ingenuity to achieve high-level goals. For instance, the cohort was tasked with building a device with LEGOs that they could use to biopsy a grape suspended in Jell-O.

    The program showed her how much creativity is involved in engineering and computer science, and piqued her interest in pursuing an academic career.

    “But when I got into college at Princeton, I could not decide — math, physics, computer science — they all seemed super-cool. I wanted to do all of it,” she says.

    She settled on pursuing an undergraduate math degree but took all the physics and computer science courses she could cram into her schedule.

    Digging into data analysis

    After receiving a Marshall Scholarship, Broderick spent two years at Cambridge University in the United Kingdom, earning a master of advanced study in mathematics and a master of philosophy in physics.

    In the UK, she took a number of statistics and data analysis classes, including her first class on Bayesian data analysis in the field of machine learning.

    It was a transformative experience, she recalls.

    “During my time in the U.K., I realized that I really like solving real-world problems that matter to people, and Bayesian inference was being used in some of the most important problems out there,” she says.

    Back in the U.S., Broderick headed to the University of California at Berkeley, where she joined the lab of Professor Michael I. Jordan as a grad student. She earned a PhD in statistics with a focus on Bayesian data analysis. 

    She decided to pursue a career in academia and was drawn to MIT by the collaborative nature of the EECS department and by how passionate and friendly her would-be colleagues were.

    Her first impressions panned out, and Broderick says she has found a community at MIT that helps her be creative and explore hard, impactful problems with wide-ranging applications.

    “I’ve been lucky to work with a really amazing set of students and postdocs in my lab — brilliant and hard-working people whose hearts are in the right place,” she says.

    One of her team’s recent projects involves a collaboration with an economist who studies the use of microcredit, or the lending of small amounts of money at very low interest rates, in impoverished areas.

    The goal of microcredit programs is to raise people out of poverty. Economists run randomized control trials of villages in a region that receive or don’t receive microcredit. They want to generalize the study results, predicting the expected outcome if one applies microcredit to other villages outside of their study.

    But Broderick and her collaborators have found that results of some microcredit studies can be very brittle. Removing one or a few data points from the dataset can completely change the results. One issue is that researchers often use empirical averages, where a few very high or low data points can skew the results.

    Using machine learning, she and her collaborators developed a method that can determine how many data points must be dropped to change the substantive conclusion of the study. With their tool, a scientist can see how brittle the results are.

    “Sometimes dropping a very small fraction of data can change the major results of a data analysis, and then we might worry how far those conclusions generalize to new scenarios. Are there ways we can flag that for people? That is what we are getting at with this work,” she explains.

    At the same time, she is continuing to collaborate with researchers in a range of fields, such as genetics, to understand the pros and cons of different machine-learning techniques and other data analysis tools.

    Happy trails

    Exploration is what drives Broderick as a researcher, and it also fuels one of her passions outside the lab. She and her husband enjoy collecting patches they earn by hiking all the trails in a park or trail system.

    “I think my hobby really combines my interests of being outdoors and spreadsheets,” she says. “With these hiking patches, you have to explore everything and then you see areas you wouldn’t normally see. It is adventurous, in that way.”

    They’ve discovered some amazing hikes they would never have known about, but also embarked on more than a few “total disaster hikes,” she says. But each hike, whether a hidden gem or an overgrown mess, offers its own rewards.

    And just like in her research, curiosity, open-mindedness, and a passion for problem-solving have never led her astray. More

  • in

    Startup accelerates progress toward light-speed computing

    Our ability to cram ever-smaller transistors onto a chip has enabled today’s age of ubiquitous computing. But that approach is finally running into limits, with some experts declaring an end to Moore’s Law and a related principle, known as Dennard’s Scaling.

    Those developments couldn’t be coming at a worse time. Demand for computing power has skyrocketed in recent years thanks in large part to the rise of artificial intelligence, and it shows no signs of slowing down.

    Now Lightmatter, a company founded by three MIT alumni, is continuing the remarkable progress of computing by rethinking the lifeblood of the chip. Instead of relying solely on electricity, the company also uses light for data processing and transport. The company’s first two products, a chip specializing in artificial intelligence operations and an interconnect that facilitates data transfer between chips, use both photons and electrons to drive more efficient operations.

    “The two problems we are solving are ‘How do chips talk?’ and ‘How do you do these [AI] calculations?’” Lightmatter co-founder and CEO Nicholas Harris PhD ’17 says. “With our first two products, Envise and Passage, we’re addressing both of those questions.”

    In a nod to the size of the problem and the demand for AI, Lightmatter raised just north of $300 million in 2023 at a valuation of $1.2 billion. Now the company is demonstrating its technology with some of the largest technology companies in the world in hopes of reducing the massive energy demand of data centers and AI models.

    “We’re going to enable platforms on top of our interconnect technology that are made up of hundreds of thousands of next-generation compute units,” Harris says. “That simply wouldn’t be possible without the technology that we’re building.”

    From idea to $100K

    Prior to MIT, Harris worked at the semiconductor company Micron Technology, where he studied the fundamental devices behind integrated chips. The experience made him see how the traditional approach for improving computer performance — cramming more transistors onto each chip — was hitting its limits.

    “I saw how the roadmap for computing was slowing, and I wanted to figure out how I could continue it,” Harris says. “What approaches can augment computers? Quantum computing and photonics were two of those pathways.”

    Harris came to MIT to work on photonic quantum computing for his PhD under Dirk Englund, an associate professor in the Department of Electrical Engineering and Computer Science. As part of that work, he built silicon-based integrated photonic chips that could send and process information using light instead of electricity.

    The work led to dozens of patents and more than 80 research papers in prestigious journals like Nature. But another technology also caught Harris’s attention at MIT.

    “I remember walking down the hall and seeing students just piling out of these auditorium-sized classrooms, watching relayed live videos of lectures to see professors teach deep learning,” Harris recalls, referring to the artificial intelligence technique. “Everybody on campus knew that deep learning was going to be a huge deal, so I started learning more about it, and we realized that the systems I was building for photonic quantum computing could actually be leveraged to do deep learning.”

    Harris had planned to become a professor after his PhD, but he realized he could attract more funding and innovate more quickly through a startup, so he teamed up with Darius Bunandar PhD ’18, who was also studying in Englund’s lab, and Thomas Graham MBA ’18. The co-founders successfully launched into the startup world by winning the 2017 MIT $100K Entrepreneurship Competition.

    Seeing the light

    Lightmatter’s Envise chip takes the part of computing that electrons do well, like memory, and combines it with what light does well, like performing the massive matrix multiplications of deep-learning models.

    “With photonics, you can perform multiple calculations at the same time because the data is coming in on different colors of light,” Harris explains. “In one color, you could have a photo of a dog. In another color, you could have a photo of a cat. In another color, maybe a tree, and you could have all three of those operations going through the same optical computing unit, this matrix accelerator, at the same time. That drives up operations per area, and it reuses the hardware that’s there, driving up energy efficiency.”

    Passage takes advantage of light’s latency and bandwidth advantages to link processors in a manner similar to how fiber optic cables use light to send data over long distances. It also enables chips as big as entire wafers to act as a single processor. Sending information between chips is central to running the massive server farms that power cloud computing and run AI systems like ChatGPT.

    Both products are designed to bring energy efficiencies to computing, which Harris says are needed to keep up with rising demand without bringing huge increases in power consumption.

    “By 2040, some predict that around 80 percent of all energy usage on the planet will be devoted to data centers and computing, and AI is going to be a huge fraction of that,” Harris says. “When you look at computing deployments for training these large AI models, they’re headed toward using hundreds of megawatts. Their power usage is on the scale of cities.”

    Lightmatter is currently working with chipmakers and cloud service providers for mass deployment. Harris notes that because the company’s equipment runs on silicon, it can be produced by existing semiconductor fabrication facilities without massive changes in process.

    The ambitious plans are designed to open up a new path forward for computing that would have huge implications for the environment and economy.

    “We’re going to continue looking at all of the pieces of computers to figure out where light can accelerate them, make them more energy efficient, and faster, and we’re going to continue to replace those parts,” Harris says. “Right now, we’re focused on interconnect with Passage and on compute with Envise. But over time, we’re going to build out the next generation of computers, and it’s all going to be centered around light.” More

  • in

    New AI model could streamline operations in a robotic warehouse

    Hundreds of robots zip back and forth across the floor of a colossal robotic warehouse, grabbing items and delivering them to human workers for packing and shipping. Such warehouses are increasingly becoming part of the supply chain in many industries, from e-commerce to automotive production.

    However, getting 800 robots to and from their destinations efficiently while keeping them from crashing into each other is no easy task. It is such a complex problem that even the best path-finding algorithms struggle to keep up with the breakneck pace of e-commerce or manufacturing. 

    In a sense, these robots are like cars trying to navigate a crowded city center. So, a group of MIT researchers who use AI to mitigate traffic congestion applied ideas from that domain to tackle this problem.

    They built a deep-learning model that encodes important information about the warehouse, including the robots, planned paths, tasks, and obstacles, and uses it to predict the best areas of the warehouse to decongest to improve overall efficiency.

    Their technique divides the warehouse robots into groups, so these smaller groups of robots can be decongested faster with traditional algorithms used to coordinate robots. In the end, their method decongests the robots nearly four times faster than a strong random search method.

    In addition to streamlining warehouse operations, this deep learning approach could be used in other complex planning tasks, like computer chip design or pipe routing in large buildings.

    “We devised a new neural network architecture that is actually suitable for real-time operations at the scale and complexity of these warehouses. It can encode hundreds of robots in terms of their trajectories, origins, destinations, and relationships with other robots, and it can do this in an efficient manner that reuses computation across groups of robots,” says Cathy Wu, the Gilbert W. Winslow Career Development Assistant Professor in Civil and Environmental Engineering (CEE), and a member of a member of the Laboratory for Information and Decision Systems (LIDS) and the Institute for Data, Systems, and Society (IDSS).

    Wu, senior author of a paper on this technique, is joined by lead author Zhongxia Yan, a graduate student in electrical engineering and computer science. The work will be presented at the International Conference on Learning Representations.

    Robotic Tetris

    From a bird’s eye view, the floor of a robotic e-commerce warehouse looks a bit like a fast-paced game of “Tetris.”

    When a customer order comes in, a robot travels to an area of the warehouse, grabs the shelf that holds the requested item, and delivers it to a human operator who picks and packs the item. Hundreds of robots do this simultaneously, and if two robots’ paths conflict as they cross the massive warehouse, they might crash.

    Traditional search-based algorithms avoid potential crashes by keeping one robot on its course and replanning a trajectory for the other. But with so many robots and potential collisions, the problem quickly grows exponentially.

    “Because the warehouse is operating online, the robots are replanned about every 100 milliseconds. That means that every second, a robot is replanned 10 times. So, these operations need to be very fast,” Wu says.

    Because time is so critical during replanning, the MIT researchers use machine learning to focus the replanning on the most actionable areas of congestion — where there exists the most potential to reduce the total travel time of robots.

    Wu and Yan built a neural network architecture that considers smaller groups of robots at the same time. For instance, in a warehouse with 800 robots, the network might cut the warehouse floor into smaller groups that contain 40 robots each.

    Then, it predicts which group has the most potential to improve the overall solution if a search-based solver were used to coordinate trajectories of robots in that group.

    An iterative process, the overall algorithm picks the most promising robot group with the neural network, decongests the group with the search-based solver, then picks the next most promising group with the neural network, and so on.

    Considering relationships

    The neural network can reason about groups of robots efficiently because it captures complicated relationships that exist between individual robots. For example, even though one robot may be far away from another initially, their paths could still cross during their trips.

    The technique also streamlines computation by encoding constraints only once, rather than repeating the process for each subproblem. For instance, in a warehouse with 800 robots, decongesting a group of 40 robots requires holding the other 760 robots as constraints. Other approaches require reasoning about all 800 robots once per group in each iteration.

    Instead, the researchers’ approach only requires reasoning about the 800 robots once across all groups in each iteration.

    “The warehouse is one big setting, so a lot of these robot groups will have some shared aspects of the larger problem. We designed our architecture to make use of this common information,” she adds.

    They tested their technique in several simulated environments, including some set up like warehouses, some with random obstacles, and even maze-like settings that emulate building interiors.

    By identifying more effective groups to decongest, their learning-based approach decongests the warehouse up to four times faster than strong, non-learning-based approaches. Even when they factored in the additional computational overhead of running the neural network, their approach still solved the problem 3.5 times faster.

    In the future, the researchers want to derive simple, rule-based insights from their neural model, since the decisions of the neural network can be opaque and difficult to interpret. Simpler, rule-based methods could also be easier to implement and maintain in actual robotic warehouse settings.

    “This approach is based on a novel architecture where convolution and attention mechanisms interact effectively and efficiently. Impressively, this leads to being able to take into account the spatiotemporal component of the constructed paths without the need of problem-specific feature engineering. The results are outstanding: Not only is it possible to improve on state-of-the-art large neighborhood search methods in terms of quality of the solution and speed, but the model generalizes to unseen cases wonderfully,” says Andrea Lodi, the Andrew H. and Ann R. Tisch Professor at Cornell Tech, and who was not involved with this research.

    This work was supported by Amazon and the MIT Amazon Science Hub. More

  • in

    “We offer another place for knowledge”

    In the Dzaleka Refugee Camp in Malawi, Jospin Hassan didn’t have access to the education opportunities he sought. So, he decided to create his own. 

    Hassan knew the booming fields of data science and artificial intelligence could bring job opportunities to his community and help solve local challenges. After earning a spot in the 2020-21 cohort of the Certificate Program in Computer and Data Science from MIT Refugee Action Hub (ReACT), Hassan started sharing MIT knowledge and skills with other motivated learners in Dzaleka.

    MIT ReACT is now Emerging Talent, part of the Jameel World Education Lab (J-WEL) at MIT Open Learning. Currently serving its fifth cohort of global learners, Emerging Talent’s year-long certificate program incorporates high-quality computer science and data analysis coursework from MITx, professional skill building, experiential learning, apprenticeship work, and opportunities for networking with MIT’s global community of innovators. Hassan’s cohort honed their leadership skills through interactive online workshops with J-WEL and the 10-week online MIT Innovation Leadership Bootcamp. 

    “My biggest takeaway was networking, collaboration, and learning from each other,” Hassan says.

    Today, Hassan’s organization ADAI Circle offers mentorship and education programs for youth and other job seekers in the Dzaleka Refugee Camp. The curriculum encourages hands-on learning and collaboration.

    Launched in 2020, ADAI Circle aims to foster job creation and reduce poverty in Malawi through technology and innovation. In addition to their classes in data science, AI, software development, and hardware design, their Innovation Hub offers internet access to anyone in need. 

    Doing something different in the community

    Hassan first had the idea for his organization in 2018 when he reached a barrier in his own education journey. There were several programs in the Dzaleka Refugee Camp teaching learners how to code websites and mobile apps, but Hassan felt that they were limited in scope. 

    “We had good devices and internet access,” he says, “but I wanted to learn something new.” 

    Teaming up with co-founder Patrick Byamasu, Hassan and Byamasu set their sights on the longevity of AI and how that might create more jobs for people in their community. “The world is changing every day, and data scientists are in a higher demand today in various companies,” Hassan says. “For this reason, I decided to expand and share the knowledge that I acquired with my fellow refugees and the surrounding villages.”

    ADAI Circle draws inspiration from Hassan’s own experience with MIT Emerging Talent coursework, community, and training opportunities. For example, the MIT Bootcamps model is now standard practice for ADAI Circle’s annual hackathon. Hassan first introduced the hackathon to ADAI Circle students as part of his final experiential learning project of the Emerging Talent certificate program. 

    ADAI Circle’s annual hackathon is now an interactive — and effective — way to select students who will most benefit from its programs. The local schools’ curricula, Hassan says, might not provide enough of an academic challenge. “We can’t teach everyone and accommodate everyone because there are a lot of schools,” Hassan says, “but we offer another place for knowledge.” 

    The hackathon helps students develop data science and robotics skills. Before they start coding, students have to convince ADAI Circle teachers that their designs are viable, answering questions like, “What problem are you solving?” and “How will this help the community?” A community-oriented mindset is just as important to the curriculum.

    In addition to the practical skills Hassan gained from Emerging Talent, he leveraged the program’s network to help his community. Thanks to a social media connection Hassan made with the nongovernmental organization Give Internet after one of Emerging Talent’s virtual events, Give Internet brought internet access to ADAI Circle.

    Bridging the AI gap to unmet communities

    In 2023, ADAI Circle connected with another MIT Open Learning program, Responsible AI for Social Empowerment and Education (RAISE), which led to a pilot test of a project-based AI curriculum for middle school students. The Responsible AI for Computational Action (RAICA) curriculum equipped ADAI Circle students with AI skills for chatbots and natural language processing. 

    “I liked that program because it was based on what we’re teaching at the center,” Hassan says, speaking of his organization’s mission of bridging the AI gap to reach unmet communities.

    The RAICA curriculum was designed by education experts at MIT Scheller Teacher Education Program (STEP Lab) and AI experts from MIT Personal Robots group and MIT App Inventor. ADAI Circle teachers gave detailed feedback about the pilot to the RAICA team. During weekly meetings with Glenda Stump, education research scientist for RAICA and J-WEL, and Angela Daniel, teacher development specialist for RAICA, the teachers discussed their experiences, prepared for upcoming lessons, and translated the learning materials in real time. 

    “We are trying to create a curriculum that’s accessible worldwide and to students who typically have little or no access to technology,” says Mary Cate Gustafson-Quiett, curriculum design manager at STEP Lab and project manager for RAICA. “Working with ADAI and students in a refugee camp challenged us to design in more culturally and technologically inclusive ways.”

    Gustafson-Quiett says the curriculum feedback from ADAI Circle helped inform how RAICA delivers teacher development resources to accommodate learning environments with limited internet access. “They also exposed places where our team’s western ideals, specifically around individualism, crept into activities in the lesson and contrasted with their more communal cultural beliefs,” she says.

    Eager to introduce more MIT-developed AI resources, Hassan also shared MIT RAISE’s Day of AI curricula with ADAI Circle teachers. The new ChatGPT module gave students the chance to level up their chatbot programming skills that they gained from the RAICA module. Some of the advanced students are taking initiative to use ChatGPT API to create their own projects in education.

    “We don’t want to tell them what to do, we want them to come up with their own ideas,” Hassan says.

    Although ADAI Circle faces many challenges, Hassan says his team is addressing them one by one. Last year, they didn’t have electricity in their Innovation Hub, but they solved that. This year, they achieved a stable internet connection that’s one of the fastest in Malawi. Next up, they are hoping to secure more devices for their students, create more jobs, and add additional hubs throughout the community. The work is never done, but Hassan is starting to see the impact that ADAI Circle is making. 

    “For those who want to learn data science, let’s let them learn,” Hassan says. More

  • in

    Automated method helps researchers quantify uncertainty in their predictions

    Pollsters trying to predict presidential election results and physicists searching for distant exoplanets have at least one thing in common: They often use a tried-and-true scientific technique called Bayesian inference.

    Bayesian inference allows these scientists to effectively estimate some unknown parameter — like the winner of an election — from data such as poll results. But Bayesian inference can be slow, sometimes consuming weeks or even months of computation time or requiring a researcher to spend hours deriving tedious equations by hand. 

    Researchers from MIT and elsewhere have introduced an optimization technique that speeds things up without requiring a scientist to do a lot of additional work. Their method can achieve more accurate results faster than another popular approach for accelerating Bayesian inference.

    Using this new automated technique, a scientist could simply input their model and then the optimization method does all the calculations under the hood to provide an approximation of some unknown parameter. The method also offers reliable uncertainty estimates that can help a researcher understand when to trust its predictions.

    This versatile technique could be applied to a wide array of scientific quandaries that incorporate Bayesian inference. For instance, it could be used by economists studying the impact of microcredit loans in developing nations or sports analysts using a model to rank top tennis players.

    “When you actually dig into what people are doing in the social sciences, physics, chemistry, or biology, they are often using a lot of the same tools under the hood. There are so many Bayesian analyses out there. If we can build a really great tool that makes these researchers lives easier, then we can really make a difference to a lot of people in many different research areas,” says senior author Tamara Broderick, an associate professor in MIT’s Department of Electrical Engineering and Computer Science (EECS) and a member of the Laboratory for Information and Decision Systems and the Institute for Data, Systems, and Society.

    Broderick is joined on the paper by co-lead authors Ryan Giordano, an assistant professor of statistics at the University of California at Berkeley; and Martin Ingram, a data scientist at the AI company KONUX. The paper was recently published in the Journal of Machine Learning Research.

    Faster results

    When researchers seek a faster form of Bayesian inference, they often turn to a technique called automatic differentiation variational inference (ADVI), which is often both fast to run and easy to use.

    But Broderick and her collaborators have found a number of practical issues with ADVI. It has to solve an optimization problem and can do so only approximately. So, ADVI can still require a lot of computation time and user effort to determine whether the approximate solution is good enough. And once it arrives at a solution, it tends to provide poor uncertainty estimates.

    Rather than reinventing the wheel, the team took many ideas from ADVI but turned them around to create a technique called deterministic ADVI (DADVI) that doesn’t have these downsides.

    With DADVI, it is very clear when the optimization is finished, so a user won’t need to spend extra computation time to ensure that the best solution has been found. DADVI also permits the incorporation of more powerful optimization methods that give it an additional speed and performance boost.

    Once it reaches a result, DADVI is set up to allow the use of uncertainty corrections. These corrections make its uncertainty estimates much more accurate than those of ADVI.

    DADVI also enables the user to clearly see how much error they have incurred in the approximation to the optimization problem. This prevents a user from needlessly running the optimization again and again with more and more resources to try and reduce the error.

    “We wanted to see if we could live up to the promise of black-box inference in the sense of, once the user makes their model, they can just run Bayesian inference and don’t have to derive everything by hand, they don’t need to figure out when to stop their algorithm, and they have a sense of how accurate their approximate solution is,” Broderick says.

    Defying conventional wisdom

    DADVI can be more effective than ADVI because it uses an efficient approximation method, called sample average approximation, which estimates an unknown quantity by taking a series of exact steps.

    Because the steps along the way are exact, it is clear when the objective has been reached. Plus, getting to that objective typically requires fewer steps.

    Often, researchers expect sample average approximation to be more computationally intensive than a more popular method, known as stochastic gradient, which is used by ADVI. But Broderick and her collaborators showed that, in many applications, this is not the case.

    “A lot of problems really do have special structure, and you can be so much more efficient and get better performance by taking advantage of that special structure. That is something we have really seen in this paper,” she adds.

    They tested DADVI on a number of real-world models and datasets, including a model used by economists to evaluate the effectiveness of microcredit loans and one used in ecology to determine whether a species is present at a particular site.

    Across the board, they found that DADVI can estimate unknown parameters faster and more reliably than other methods, and achieves as good or better accuracy than ADVI. Because it is easier to use than other techniques, DADVI could offer a boost to scientists in a wide variety of fields.

    In the future, the researchers want to dig deeper into correction methods for uncertainty estimates so they can better understand why these corrections can produce such accurate uncertainties, and when they could fall short.

    “In applied statistics, we often have to use approximate algorithms for problems that are too complex or high-dimensional to allow exact solutions to be computed in reasonable time. This new paper offers an interesting set of theory and empirical results that point to an improvement in a popular existing approximate algorithm for Bayesian inference,” says Andrew Gelman ’85, ’86, a professor of statistics and political science at Columbia University, who was not involved with the study. “As one of the team involved in the creation of that earlier work, I’m happy to see our algorithm superseded by something more stable.”

    This research was supported by a National Science Foundation CAREER Award and the U.S. Office of Naval Research.  More