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      Meet the 2022-23 Accenture Fellows

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      Launched in October 2020, the MIT and Accenture Convergence Initiative for Industry and Technology underscores the ways in which industry and technology can collaborate to spur innovation. The five-year initiative aims to achieve its mission through research, education, and fellowships. To that end, Accenture has once again awarded five annual fellowships to MIT graduate students working on research in industry and technology convergence who are underrepresented, including by race, ethnicity, and gender.This year’s Accenture Fellows work across research areas including telemonitoring, human-computer interactions, operations research,  AI-mediated socialization, and chemical transformations. Their research covers a wide array of projects, including designing low-power processing hardware for telehealth applications; applying machine learning to streamline and improve business operations; improving mental health care through artificial intelligence; and using machine learning to understand the environmental and health consequences of complex chemical reactions.As part of the application process, student nominations were invited from each unit within the School of Engineering, as well as from the Institute’s four other schools and the MIT Schwarzman College of Computing. Five exceptional students were selected as fellows for the initiative’s third year.Drew Buzzell is a doctoral candidate in electrical engineering and computer science whose research concerns telemonitoring, a fast-growing sphere of telehealth in which information is collected through internet-of-things (IoT) connected devices and transmitted to the cloud. Currently, the high volume of information involved in telemonitoring — and the time and energy costs of processing it — make data analysis difficult. Buzzell’s work is focused on edge computing, a new computing architecture that seeks to address these challenges by managing data closer to the source, in a distributed network of IoT devices. Buzzell earned his BS in physics and engineering science and his MS in engineering science from the Pennsylvania State University.

      Mengying (Cathy) Fang is a master’s student in the MIT School of Architecture and Planning. Her research focuses on augmented reality and virtual reality platforms. Fang is developing novel sensors and machine components that combine computation, materials science, and engineering. Moving forward, she will explore topics including soft robotics techniques that could be integrated with clothes and wearable devices and haptic feedback in order to develop interactions with digital objects. Fang earned a BS in mechanical engineering and human-computer interaction from Carnegie Mellon University.

      Xiaoyue Gong is a doctoral candidate in operations research at the MIT Sloan School of Management. Her research aims to harness the power of machine learning and data science to reduce inefficiencies in the operation of businesses, organizations, and society. With the support of an Accenture Fellowship, Gong seeks to find solutions to operational problems by designing reinforcement learning methods and other machine learning techniques to embedded operational problems. Gong earned a BS in honors mathematics and interactive media arts from New York University.

      Ruby Liu is a doctoral candidate in medical engineering and medical physics. Their research addresses the growing pandemic of loneliness among older adults, which leads to poor health outcomes and presents particularly high risks for historically marginalized people, including members of the LGBTQ+ community and people of color. Liu is designing a network of interconnected AI agents that foster connections between user and agent, offering mental health care while strengthening and facilitating human-human connections. Liu received a BS in biomedical engineering from Johns Hopkins University.

      Joules Provenzano is a doctoral candidate in chemical engineering. Their work integrates machine learning and liquid chromatography-high resolution mass spectrometry (LC-HRMS) to improve our understanding of complex chemical reactions in the environment. As an Accenture Fellow, Provenzano will build upon recent advances in machine learning and LC-HRMS, including novel algorithms for processing real, experimental HR-MS data and new approaches in extracting structure-transformation rules and kinetics. Their research could speed the pace of discovery in the chemical sciences and benefits industries including oil and gas, pharmaceuticals, and agriculture. Provenzano earned a BS in chemical engineering and international and global studies from the Rochester Institute of Technology. More

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      3 Questions: Why cybersecurity is on the agenda for corporate boards of directors

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      Organizations of every size and in every industry are vulnerable to cybersecurity risks — a dynamic landscape of threats and vulnerabilities and a corresponding overload of possible mitigating controls. MIT Senior Lecturer Keri Pearlson, who is also the executive director of the research consortium Cybersecurity at MIT Sloan (CAMS) and an instructor for the new MIT Sloan Executive Education course Cybersecurity Governance for the Board of Directors, knows how business can get ahead of this risk. Here, she describes the current threat and explores how boards can mitigate their risk against cybercrime.

      Q: What does the current state of cyberattacks mean for businesses in 2023?

      A: Last year we were discussing how the pandemic heightened fear, uncertainty, doubt and chaos, opening new doors for malicious actors to do their cyber mischief in our organizations and our families. We saw an increase in ransomware and other cyber attacks, and we saw an increase in concern from operating executives and board of directors wondering how to keep the organization secure. Since then, we have seen a continued escalation of cyber incidents, many of which no longer make the headlines unless they are wildly unique, damaging, or different than previous incidents. For every new technology that cybersecurity professionals invent, it’s only a matter of time until malicious actors find a way around it. New leadership approaches are needed for 2023 as we move into the next phase of securing our organizations.

      In great part, this means ensuring deep cybersecurity competencies on our boards of directors. Cyber risk is so significant that a responsible board can no longer ignore it or just delegate it to risk management experts. In fact, an organization’s board of directors holds a uniquely vital role in safeguarding data and systems for the future because of their fiduciary responsibility to shareholders and their responsibility to oversee and mitigate business risk.

      As these cyber threats increase, and as companies bolster their cybersecurity budgets accordingly, the regulatory community is also advancing new requirements of companies. In March of this year, the SEC issued a proposed rule titled Cybersecurity Risk Management, Strategy, Governance, and Incident Disclosure. In it, the SEC describes its intention to require public companies to disclose whether their boards have members with cybersecurity expertise. Specifically, registrants will be required to disclose whether the entire board, a specific board member, or a board committee is responsible for the oversight of cyber risks; the processes by which the board is informed about cyber risks, and the frequency of its discussions on this topic; and whether and how the board or specified board committee considers cyber risks as part of its business strategy, risk management, and financial oversight.

      Q: How can boards help their organizations mitigate cyber risk?

      A: According to the studies I’ve conducted with my CAMS colleagues, most organizations focus on cyber protection rather than cyber resilience, and we believe that is a mistake. A company that invests only in protection is not managing the risk associated with getting up and running again in the event of a cyber incident, and they are not going to be able to respond appropriately to new regulations, either. Resiliency means having a practical plan for recovery and business continuation.

      Certainly, protection is part of the resilience equation, but if the pandemic taught us anything, it taught us that resilience is the ability to weather an attack and recover quickly with minimal impact to our operations. The ultimate goal of a cyber-resilient organization would be zero disruption from a cyber breach — no impact on operations, finances, technologies, supply chain or reputation. Board members should ask, What would it take for this to be the case? And they should ensure that executives and managers have made proper and appropriate preparations to respond and recover.

      Being a knowledgeable board member does not mean becoming a cybersecurity expert, but it does mean understanding basic concepts, risks, frameworks, and approaches. And it means having the ability to assess whether management appropriately comprehends related threats, has an appropriate cyber strategy, and can measure its effectiveness. Board members today require focused training on these critical areas to carry out their mission. Unfortunately, many enterprises fail to leverage their boards of directors in this capacity or prepare board members to actively contribute to strategy, protocols, and emergency action plans.

      Alongside my CAMS colleagues Stuart Madnick and Kevin Powers, I’m teaching a new  MIT Sloan Executive Education course, Cybersecurity Governance for the Board of Directors, designed to help organizations and their boards get up to speed. Participants will explore the board’s role in cybersecurity, as well as breach planning, response, and mitigation. And we will discuss the impact and requirements of the many new regulations coming forward, not just from the SEC, but also White House, Congress, and most states and countries around the world, which are imposing more high-level responsibilities on companies.

      Q: What are some examples of how companies, and specifically boards of directors, have successfully upped their cybersecurity game?

      A: To ensure boardroom skills reflect the patterns of the marketplace, companies such as FedEx, Hasbro, PNC, and UPS have transformed their approach to governing cyber risk, starting with board cyber expertise. In companies like these, building resiliency started with a clear plan — from the boardroom — built on business and economic analysis.

      In one company we looked at, the CEO realized his board was not well versed in the business context or financial exposure risk from a cyber attack, so he hired a third-party consulting firm to conduct a cybersecurity maturity assessment. The company CISO presented the results of the report to the enterprise risk management subcommittee, creating a productive dialogue around the business and financial impact of different investments in cybersecurity.  

      Another organization focused their board on the alignment of their cybersecurity program and operational risk. The CISO, chief risk officer, and board collaborated to understand the exposure of the organization from a risk perspective, resulting in optimizing their cyber insurance policy to mitigate the newly understood risk.

      One important takeaway from these examples is the importance of using the language of risk, resiliency, and reputation to bridge the gaps between technical cybersecurity needs and the oversight responsibilities executed by boards. Boards need to understand the financial exposure resulting from cyber risk, not just the technical components typically found in cyber presentations.

      Cyber risk is not going away. It’s escalating and becoming more sophisticated every day. Getting your board “on board” is key to meeting new guidelines, providing sufficient oversight to cybersecurity plans, and making organizations more resilient. More

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      Celebrating open data

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      The inaugural MIT Prize for Open Data, which included a $2,500 cash prize, was recently awarded to 10 individual and group research projects. Presented jointly by the School of Science and the MIT Libraries, the prize recognizes MIT-affiliated researchers who make their data openly accessible and reusable by others. The prize winners and 16 honorable mention recipients were honored at the Open Data @ MIT event held Oct. 28 at Hayden Library. 

      “By making data open, researchers create opportunities for novel uses of their data and for new insights to be gleaned,” says Chris Bourg, director of MIT Libraries. “Open data accelerates scholarly progress and discovery, advances equity in scholarly participation, and increases transparency, replicability, and trust in science.” 

      Recognizing shared values

      Spearheaded by Bourg and Rebecca Saxe, associate dean of the School of Science and John W. Jarve (1978) Professor of Brain and Cognitive Sciences, the MIT Prize for Open Data was launched to highlight the value of open data at MIT and to encourage the next generation of researchers. Nominations were solicited from across the Institute, with a focus on trainees: research technicians, undergraduate or graduate students, or postdocs.

      “By launching an MIT-wide prize and event, we aimed to create visibility for the scholars who create, use, and advocate for open data,” says Saxe. “Highlighting this research and creating opportunities for networking would also help open-data advocates across campus find each other.” 

      Recognizing researchers who share data was also one of the recommendations of the Ad Hoc Task Force on Open Access to MIT’s Research, which Bourg co-chaired with Hal Abelson, Class of 1922 Professor, Department of Electrical Engineering and Computer Science. An annual award was one of the strategies put forth by the task force to further the Institute’s mission to disseminate the fruits of its research and scholarship as widely as possible.

      Strong competition

      Winners and honorable mentions were chosen from more than 70 nominees, representing all five schools, the MIT Schwarzman College of Computing, and several research centers across MIT. A committee composed of faculty, staff, and a graduate student made the selections:

      Yunsie Chung, graduate student in the Department of Chemical Engineering, won for SolProp, the largest open-source dataset with temperature-dependent solubility values of organic compounds. 
      Matthew Groh, graduate student, MIT Media Lab, accepted on behalf of the team behind the Fitzpatrick 17k dataset, an open dataset consisting of nearly 17,000 images of skin disease alongside skin disease and skin tone annotations. 
      Tom Pollard, research scientist at the Institute for Medical Engineering and Science, accepted on behalf of the PhysioNet team. This data-sharing platform enables thousands of clinical and machine-learning research studies each year and allows researchers to share sensitive resources that would not be possible through typical data sharing platforms. 
      Joseph Replogle, graduate student with the Whitehead Institute for Biomedical Research, was recognized for the Genome-wide Perturb-seq dataset, the largest publicly available, single-cell transcriptional dataset collected to date. 
      Pedro Reynolds-Cuéllar, graduate student with the MIT Media Lab/Art, Culture, and Technology, and Diana Duarte, co-founder at Diversa, won for Retos, an open-data platform for detailed documentation and sharing of local innovations from under-resourced settings. 
      Maanas Sharma, an undergraduate student, led States of Emergency, a nationwide project analyzing and grading the responses of prison systems to Covid-19 using data scraped from public databases and manually collected data. 
      Djuna von Maydell, graduate student in the Department of Brain and Cognitive Sciences, created the first publicly available dataset of single-cell gene expression from postmortem human brain tissue of patients who are carriers of APOE4, the major Alzheimer’s disease risk gene. 
      Raechel Walker, graduate researcher in the MIT Media Lab, and her collaborators created a Data Activism Curriculum for high school students through the Mayor’s Summer Youth Employment Program in Cambridge, Massachusetts. Students learned how to use data science to recognize, mitigate, and advocate for people who are disproportionately impacted by systemic inequality. 
      Suyeol Yun, graduate student in the Department of Political Science, was recognized for DeepWTO, a project creating open data for use in legal natural language processing research using cases from the World Trade Organization. 
      Jonathan Zheng, graduate student in the Department of Chemical Engineering, won for an open IUPAC dataset for acid dissociation constants, or “pKas,” physicochemical properties that govern how acidic a chemical is in a solution.
      A full list of winners and honorable mentions is available on the Open Data @ MIT website.

      A campus-wide celebration

      Awards were presented at a celebratory event held in the Nexus in Hayden Library during International Open Access Week. School of Science Dean Nergis Mavalvala kicked off the program by describing the long and proud history of open scholarship at MIT, citing the Institute-wide faculty open access policy and the launch of the open-source digital repository DSpace. “When I was a graduate student, we were trying to figure out how to share our theses during the days of the nascent internet,” she said, “With DSpace, MIT was figuring it out for us.” 

      The centerpiece of the program was a series of five-minute presentations from the prize winners on their research. Presenters detailed the ways they created, used, or advocated for open data, and the value that openness brings to their respective fields. Winner Djuna von Maydell, a graduate student in Professor Li-Huei Tsai’s lab who studies the genetic causes of neurodegeneration, underscored why it is important to share data, particularly data obtained from postmortem human brains. 

      “This is data generated from human brains, so every data point stems from a living, breathing human being, who presumably made this donation in the hope that we would use it to advance knowledge and uncover truth,” von Maydell said. “To maximize the probability of that happening, we have to make it available to the scientific community.” 

      MIT community members who would like to learn more about making their research data open can consult MIT Libraries’ Data Services team.  More

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      Ad hoc committee releases report on remote teaching best practices for on-campus education

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      The Ad Hoc Committee on Leveraging Best Practices from Remote Teaching for On-Campus Education has released a report that captures how instructors are weaving lessons learned from remote teaching into in-person classes. Despite the challenges imposed by teaching and learning remotely during the Covid-19 pandemic, the report says, “there were seeds planted then that, we hope, will bear fruit in the coming years.”

      “In the long run, one of the best things about having lived through our remote learning experience may be the intense and broad focus on pedagogy that it necessitated,” the report continues. “In a moment when nobody could just teach the way they had always done before, all of us had to go back to first principles and ask ourselves: What are our learning goals for our students? How can we best help them to achieve these goals?”

      The committee’s work is a direct response to one of the Refinement and Implementation Committees (RIC) formed as part of Task Force 2021 and Beyond. Led by co-chairs Krishna Rajagopal, the William A. M. Burden Professor of Physics, and Janet Rankin, director of the MIT Teaching + Learning Lab, the committee engaged with faculty and instructional staff, associate department heads, and undergraduate and graduate officers across MIT.

      The findings are distilled into four broad themes:

      Community, Well-being, and Belonging. Conversations revealed new ways that instructors cultivated these key interrelated concepts, all of which are fundamental to student learning and success. Many instructors focused more on supporting well-being and building community and belonging during the height of the pandemic precisely because the MIT community, and everyone in it, was under such great stress. Some of the resulting practices are continuing, the committee found. Examples include introducing simple gestures, such as start-of-class welcoming practices, and providing extensions and greater flexibility on student assignments. Also, many across MIT felt that the week-long Thanksgiving break offered in 2020 should become a permanent fixture in the academic calendar, because it enhances the well-being of both students and instructors at a time in the fall semester when everyone’s batteries need recharging. 
      Enhancing Engagement. The committee found a variety of practices that have enhanced engagement between students and instructors; among students; and among instructors. For example, many instructors have continued to offer some office hours on Zoom, which seems to reduce barriers to participation for many students, while offering in-person office hours for those who want to take advantage of opportunities for more open-ended conversations. Several departments increased their usage of undergraduate teaching assistants (UTAs) in ways that make students’ learning experience more engaging and give the UTAs a real teaching experience. In addition, many instructors are leveraging out-of-class communication spaces like Slack, Perusall, and Piazza so students can work together, ask questions, and share ideas. 
      Enriching and Augmenting the Learning Environment. The report presents two ways in which instructors have enhanced learning within the classroom: through blended learning and by incorporating authentic experiences. Although blended learning techniques are not new at MIT, after having made it through remote teaching many faculty have found new ways to combine synchronous in-person teaching with asynchronous activities for on-campus students, such as pre-class or pre-lab sequences of videos with exercises interspersed, take-home lab kits, auto-graded online problems that give students immediate feedback, and recorded lab experiences for subsequent review. In addition, instructors found many creative ways to make students’ learning more authentic by going on virtual field trips, using Zoom to bring experts from around the world into MIT classrooms or to enable interactions with students at other universities, and live-streaming experiments that students could not otherwise experience since they cannot be performed in a teaching lab.   
       Assessing Learning. For all its challenges, the report notes, remote teaching prompted instructors to take a step back and think about what they wanted students to learn, how to support it, and how to measure it. The committee found a variety of examples of alternatives to traditional assessments, such as papers or timed, written exams, that instructors tried during the pandemic and are continuing to use. These alternatives include shorter, more frequent, lower-stakes assessments; oral exams or debates; asynchronous, open-book/notes exams; virtual poster sessions; alternate grading schemes; and uploading paper psets and exams into Gradescope to use its logistics and rubrics to improve grading effectiveness and efficiency.
      A large portion of the report is devoted to an extensive, annotated list of best practices from remote instruction that are being used in the classroom. Interestingly, Rankin says, “so many of the strategies and practices developed and used during the pandemic are based on, and supported by, solid educational research.”

      The report concludes with one broad recommendation: that all faculty and instructors read the findings and experiment with some of the best practices in their own instruction. “Our hope is that the practices shared in the report will continue to be adopted, adapted, and expanded by members of the teaching community at MIT, and that instructors’ openness in sharing and learning from each will continue,” Rankin says.

      Two additional, specific recommendations are included in the report. First, the committee endorses the RIC 16 recommendation that a Classroom Advisory Board be created to provide strategic input grounded in evolving pedagogy about future classroom use and technology needs. In its conversations, the committee found a number of ways that remote teaching and learning have impacted students’ and instructors’ perceptions as they have returned to the classroom. For example, during the pandemic students benefited from being able to see everyone else’s faces on Zoom. As a result, some instructors would prefer classrooms that enable students to face each other, such as semi-circular classrooms instead of rectangular ones.

      More generally, the committee concluded, MIT needs classrooms with seats and tables that can be quickly and flexibly reconfigured to facilitate varying pedagogical objectives. The Classroom Advisory Board could also examine classroom technology; this includes the role of videoconferencing to create authentic engagement between MIT students and people far from campus, and blended learning that allows students to experience more of the in-classroom engagement with their peers and instructors from which the “magic of MIT” originates.

      Second, the committee recommends that an implementation group be formed to investigate the possibility of changing the MIT academic calendar to create a one-week break over Thanksgiving. “Finalizing an implementation plan will require careful consideration of various significant logistical challenges,” the report says. “However, the resulting gains to both well-being and learning from this change to the fall calendar make doing so worthwhile.”

      Rankin notes that the report findings dovetail with the recently released MIT Strategic Action Plan for Belonging, Achievement and Composition. “I believe that one of the most important things that became really apparent during remote teaching was that community, inclusion, and belonging really matter and are necessary for both learning and teaching, and that instructors can and should play a central role in creating structures and processes to support them in their classrooms and other learning environments,” she says.

      Rajagopal finds it inspiring that “during a time of intense stress — that nobody ever wants to relive — there was such an intense focus on how we teach and how our students learn that, today, in essentially every direction we look we see colleagues improving on-campus education for tomorrow. I hope that the report will help instructors across the Institute, and perhaps elsewhere, learn from each other. Its readers will see, as our committee did, new ways in which students and instructors are finding those moments, those interactions, where the magic of MIT is created.”

      In addition to the report, the co-chairs recommend two other valuable remote teaching resources: a video interview series, TLL’s Fresh Perspectives, and Open Learning’s collection of examples of how MIT faculty and instructors leveraged digital technology to support and transform teaching and learning during the heart of the pandemic. More

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      Q&A: Global challenges surrounding the deployment of AI

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      The AI Policy Forum (AIPF) is an initiative of the MIT Schwarzman College of Computing to move the global conversation about the impact of artificial intelligence from principles to practical policy implementation. Formed in late 2020, AIPF brings together leaders in government, business, and academia to develop approaches to address the societal challenges posed by the rapid advances and increasing applicability of AI.

      The co-chairs of the AI Policy Forum are Aleksander Madry, the Cadence Design Systems Professor; Asu Ozdaglar, deputy dean of academics for the MIT Schwarzman College of Computing and head of the Department of Electrical Engineering and Computer Science; and Luis Videgaray, senior lecturer at MIT Sloan School of Management and director of MIT AI Policy for the World Project. Here, they discuss talk some of the key issues facing the AI policy landscape today and the challenges surrounding the deployment of AI. The three are co-organizers of the upcoming AI Policy Forum Summit on Sept. 28, which will further explore the issues discussed here.

      Q: Can you talk about the ­ongoing work of the AI Policy Forum and the AI policy landscape generally?

      Ozdaglar: There is no shortage of discussion about AI at different venues, but conversations are often high-level, focused on questions of ethics and principles, or on policy problems alone. The approach the AIPF takes to its work is to target specific questions with actionable policy solutions and engage with the stakeholders working directly in these areas. We work “behind the scenes” with smaller focus groups to tackle these challenges and aim to bring visibility to some potential solutions alongside the players working directly on them through larger gatherings.

      Q: AI impacts many sectors, which makes us naturally worry about its trustworthiness. Are there any emerging best practices for development and deployment of trustworthy AI?

      Madry: The most important thing to understand regarding deploying trustworthy AI is that AI technology isn’t some natural, preordained phenomenon. It is something built by people. People who are making certain design decisions.

      We thus need to advance research that can guide these decisions as well as provide more desirable solutions. But we also need to be deliberate and think carefully about the incentives that drive these decisions. 

      Now, these incentives stem largely from the business considerations, but not exclusively so. That is, we should also recognize that proper laws and regulations, as well as establishing thoughtful industry standards have a big role to play here too.

      Indeed, governments can put in place rules that prioritize the value of deploying AI while being keenly aware of the corresponding downsides, pitfalls, and impossibilities. The design of such rules will be an ongoing and evolving process as the technology continues to improve and change, and we need to adapt to socio-political realities as well.

      Q: Perhaps one of the most rapidly evolving domains in AI deployment is in the financial sector. From a policy perspective, how should governments, regulators, and lawmakers make AI work best for consumers in finance?

      Videgaray: The financial sector is seeing a number of trends that present policy challenges at the intersection of AI systems. For one, there is the issue of explainability. By law (in the U.S. and in many other countries), lenders need to provide explanations to customers when they take actions deleterious in whatever way, like denial of a loan, to a customer’s interest. However, as financial services increasingly rely on automated systems and machine learning models, the capacity of banks to unpack the “black box” of machine learning to provide that level of mandated explanation becomes tenuous. So how should the finance industry and its regulators adapt to this advance in technology? Perhaps we need new standards and expectations, as well as tools to meet these legal requirements.

      Meanwhile, economies of scale and data network effects are leading to a proliferation of AI outsourcing, and more broadly, AI-as-a-service is becoming increasingly common in the finance industry. In particular, we are seeing fintech companies provide the tools for underwriting to other financial institutions — be it large banks or small, local credit unions. What does this segmentation of the supply chain mean for the industry? Who is accountable for the potential problems in AI systems deployed through several layers of outsourcing? How can regulators adapt to guarantee their mandates of financial stability, fairness, and other societal standards?

      Q: Social media is one of the most controversial sectors of the economy, resulting in many societal shifts and disruptions around the world. What policies or reforms might be needed to best ensure social media is a force for public good and not public harm?

      Ozdaglar: The role of social media in society is of growing concern to many, but the nature of these concerns can vary quite a bit — with some seeing social media as not doing enough to prevent, for example, misinformation and extremism, and others seeing it as unduly silencing certain viewpoints. This lack of unified view on what the problem is impacts the capacity to enact any change. All of that is additionally coupled with the complexities of the legal framework in the U.S. spanning the First Amendment, Section 230 of the Communications Decency Act, and trade laws.

      However, these difficulties in regulating social media do not mean that there is nothing to be done. Indeed, regulators have begun to tighten their control over social media companies, both in the United States and abroad, be it through antitrust procedures or other means. In particular, Ofcom in the U.K. and the European Union is already introducing new layers of oversight to platforms. Additionally, some have proposed taxes on online advertising to address the negative externalities caused by current social media business model. So, the policy tools are there, if the political will and proper guidance exists to implement them. More

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      New leadership at MIT’s Center for Biomedical Innovation

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      As it continues in its mission to improve global health through the development and implementation of biomedical innovation, the MIT Center for Biomedical Innovation (CBI) today announced changes to its leadership team: Stacy Springs has been named executive director, and Professor Richard Braatz has joined as the center’s new associate faculty director.

      The change in leadership comes at a time of rapid development in new therapeutic modalities, growing concern over global access to biologic medicines and healthy food, and widespread interest in applying computational tools and multi-disciplinary approaches to address long-standing biomedical challenges.

      “This marks an exciting new chapter for the CBI,” says faculty director Anthony J. Sinskey, professor of biology, who cofounded CBI in 2005. “As I look back at almost 20 years of CBI history, I see an exponential growth in our activities, educational offerings, and impact.”

      The center’s collaborative research model accelerates innovation in biotechnology and biomedical research, drawing on the expertise of faculty and researchers in MIT’s schools of Engineering and Science, the MIT Schwarzman College of Computing, and the MIT Sloan School of Management.

      Springs steps into the role of executive director having previously served as senior director of programs for CBI and as executive director of CBI’s Biomanufacturing Program and its Consortium on Adventitious Agent Contamination in Biomanufacturing (CAACB). She succeeds Gigi Hirsch, who founded the NEW Drug Development ParadIGmS (NEWDIGS) Initiative at CBI in 2009. Hirsch and NEWDIGS have now moved to Tufts Medical Center, establishing a headquarters at the new Center for Biomedical System Design within the Institute for Clinical Research and Health Policy Studies there.

      Braatz, a chemical engineer whose work is informed by mathematical modeling and computational techniques, conducts research in process data analytics, design, and control of advanced manufacturing systems.

      “It’s been great to interact with faculty from across the Institute who have complementary expertise,” says Braatz, the Edwin R. Gilliland Professor in the Department of Chemical Engineering. “Participating in CBI’s workshops has led to fruitful partnerships with companies in tackling industry-wide challenges.”

      CBI is housed under the Institute for Data Systems and Society and, specifically, the Sociotechnical Systems Research Center in the MIT Schwarzman College of Computing. CBI is home to two biomanufacturing consortia: the CAACB and the Biomanufacturing Consortium (BioMAN). Through these precompetitive collaborations, CBI researchers work with biomanufacturers and regulators to advance shared interests in biomanufacturing.

      In addition, CBI researchers are engaged in several sponsored research programs focused on integrated continuous biomanufacturing capabilities for monoclonal antibodies and vaccines, analytical technologies to measure quality and safety attributes of a variety of biologics, including gene and cell therapies, and rapid-cycle development of virus-like particle vaccines for SARS-CoV-2.

      In another significant initiative, CBI researchers are applying data analytics strategies to biomanufacturing problems. “In our smart data analytics project, we are creating new decision support tools and algorithms for biomanufacturing process control and plant-level decision-making. Further, we are leveraging machine learning and natural language processing to improve post-market surveillance studies,” says Springs.

      CBI is also working on advanced manufacturing for cell and gene therapies, among other new modalities, and is a part of the Singapore-MIT Alliance for Research and Technology – Critical Analytics for Manufacturing Personalized-Medicine (SMART CAMP). SMART CAMP is an international research effort focused on developing the analytical tools and biological understanding of critical quality attributes that will enable the manufacture and delivery of improved cell therapies to patients.

      “This is a crucial time for biomanufacturing and for innovation across the health-care value chain. The collaborative efforts of MIT researchers and consortia members will drive fundamental discovery and inform much-needed progress in industry,” says MIT Vice President for Research Maria Zuber.

      “CBI has a track record of engaging with health-care ecosystem challenges. I am confident that under the new leadership, it will continue to inspire MIT, the United States, and the entire world to improve the health of all people,” adds Daniel Huttenlocher, dean of the MIT Schwarzman College of Computing. More

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      Caspar Hare, Georgia Perakis named associate deans of Social and Ethical Responsibilities of Computing

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      Caspar Hare and Georgia Perakis have been appointed the new associate deans of the Social and Ethical Responsibilities of Computing (SERC), a cross-cutting initiative in the MIT Stephen A. Schwarzman College of Computing. Their new roles will take effect on Sept. 1.

      “Infusing social and ethical aspects of computing in academic research and education is a critical component of the college mission,” says Daniel Huttenlocher, dean of the MIT Schwarzman College of Computing and the Henry Ellis Warren Professor of Electrical Engineering and Computer Science. “I look forward to working with Caspar and Georgia on continuing to develop and advance SERC and its reach across MIT. Their complementary backgrounds and their broad connections across MIT will be invaluable to this next chapter of SERC.”

      Caspar Hare

      Hare is a professor of philosophy in the Department of Linguistics and Philosophy. A member of the MIT faculty since 2003, his main interests are in ethics, metaphysics, and epistemology. The general theme of his recent work has been to bring ideas about practical rationality and metaphysics to bear on issues in normative ethics and epistemology. He is the author of two books: “On Myself, and Other, Less Important Subjects” (Princeton University Press 2009), about the metaphysics of perspective, and “The Limits of Kindness” (Oxford University Press 2013), about normative ethics.

      Georgia Perakis

      Perakis is the William F. Pounds Professor of Management and professor of operations research, statistics, and operations management at the MIT Sloan School of Management, where she has been a faculty member since 1998. She investigates the theory and practice of analytics and its role in operations problems and is particularly interested in how to solve complex and practical problems in pricing, revenue management, supply chains, health care, transportation, and energy applications, among other areas. Since 2019, she has been the co-director of the Operations Research Center, an interdepartmental PhD program that jointly reports to MIT Sloan and the MIT Schwarzman College of Computing, a role in which she will remain. Perakis will also assume an associate dean role at MIT Sloan in recognition of her leadership.

      Hare and Perakis succeed David Kaiser, the Germeshausen Professor of the History of Science and professor of physics, and Julie Shah, the H.N. Slater Professor of Aeronautics and Astronautics, who will be stepping down from their roles at the conclusion of their three-year term on Aug. 31.

      “My deepest thanks to Dave and Julie for their tremendous leadership of SERC and contributions to the college as associate deans,” says Huttenlocher.

      SERC impact

      As the inaugural associate deans of SERC, Kaiser and Shah have been responsible for advancing a mission to incorporate humanist, social science, social responsibility, and civic perspectives into MIT’s teaching, research, and implementation of computing. In doing so, they have engaged dozens of faculty members and thousands of students from across MIT during these first three years of the initiative.

      They have brought together people from a broad array of disciplines to collaborate on crafting original materials such as active learning projects, homework assignments, and in-class demonstrations. A collection of these materials was recently published and is now freely available to the world via MIT OpenCourseWare.

      In February 2021, they launched the MIT Case Studies in Social and Ethical Responsibilities of Computing for undergraduate instruction across a range of classes and fields of study. The specially commissioned and peer-reviewed cases are based on original research and are brief by design. Three issues have been published to date and a fourth will be released later this summer. Kaiser will continue to oversee the successful new series as editor.

      Last year, 60 undergraduates, graduate students, and postdocs joined a community of SERC Scholars to help advance SERC efforts in the college. The scholars participate in unique opportunities throughout, such as the summer Experiential Ethics program. A multidisciplinary team of graduate students last winter worked with the instructors and teaching assistants of class 6.036 (Introduction to Machine Learning), MIT’s largest machine learning course, to infuse weekly labs with material covering ethical computing, data and model bias, and fairness in machine learning through SERC.

      Through efforts such as these, SERC has had a substantial impact at MIT and beyond. Over the course of their tenure, Kaiser and Shah have engaged about 80 faculty members, and more than 2,100 students took courses that included new SERC content in the last year alone. SERC’s reach extended well beyond engineering students, with about 500 exposed to SERC content through courses offered in the School of Humanities, Arts, and Social Sciences, the MIT Sloan School of Management, and the School of Architecture and Planning. More

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      in Data Management & Statistics

      Emma Gibson: Optimizing health care logistics in Africa

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      Growing up in South Africa at the turn of the century, Emma Gibson saw the rise of the HIV/AIDS epidemic and its devastating impact on her home country, where many people lacked life-saving health care. At the time, Gibson was too young to understand what a sexually transmitted infection was, but she knew that HIV was infecting millions of South Africans and AIDS was taking hundreds of thousands of lives. “As a child, I was terrified by this monster that was HIV and felt so powerless to do anything about it,” she says.

      Now, as an adult, her childhood fear of the HIV epidemic has evolved into a desire to fight it. Gibson seeks to improve health care for HIV and other diseases in regions with limited resources, including South Africa. She wants to help health care facilities in these areas to use their resources more effectively so that patients can more easily obtain care.

      To help reach her goal, Gibson sought mathematics and logistics training through higher education in South Africa. She first earned her bachelor’s degree in mathematical sciences at the University of the Witwatersrand, and then her master’s degree in operations research at Stellenbosch University. There, she learned to tackle complex decision-making problems using math, statistics, and computer simulations.

      During her master’s, Gibson studied the operational challenges faced in rural South African health care facilities by working with staff at Zithulele Hospital in the Eastern Cape, one of the country’s poorest provinces. Her research focused on ways to reduce hours-long wait times for patients seeking same-day care. In the end, she developed a software tool to model patient congestion throughout the day and optimize staff schedules accordingly, enabling the hospital to care for its patients more efficiently.

      After completing her master’s, Gibson wanted to further her education outside of South Africa and left to pursue a PhD in operations research at MIT. Upon arrival, she branched out in her research and worked on a project to improve breast cancer treatment in U.S. health care, a very different environment from what she was used to.

      Two years later, Gibson had the opportunity to return to researching health care in resource-limited settings and began working with Jónas Jónasson, an associate professor at the MIT Sloan School of Management, on a new project to improve diagnostic services in sub-Saharan Africa. For the past four years, she has been working diligently on this project in collaboration with researchers at the Indian School of Business and Northwestern University. “My love language is time,” she says. “If I’m investing a lot of time in something, I really value it.”

      Scheduling sample transport

      Diagnostic testing is an essential tool that allows medical professionals to identify new diagnoses in patients and monitor patients’ conditions as they undergo treatment. For example, people living with HIV require regular blood tests to ensure that their prescribed treatments are working effectively and provide an early warning of potential treatment failures.

      For Gibson’s current project, she’s trying to improve diagnostic services in Malawi, a landlocked country in southeast Africa. “We have the tools” to diagnose and treat diseases like HIV, she says. “But in resource-limited settings, we often lack the money, the staff, and the infrastructure to reach every patient that needs them.”

      When diagnostic testing is needed, clinicians collect samples from patients and send the samples to be tested at a laboratory, which then returns the results to the facility where the patient is treated. To move these items between facilities and laboratories, Malawi has developed a national sample transportation network. The transportation system plays an important role in linking remote, rural facilities to laboratory services and ensuring that patients in these areas can access diagnostic testing through community clinics. Samples collected at these clinics are first transported to nearby district hubs, and then forwarded to laboratories located in urban areas. Since most facilities do not have computers or communications infrastructure, laboratories print copies of test results and send them back to facilities through the same transportation process.

      The sample transportation cycle is onerous, but it’s a practical solution to a difficult problem. “During the Covid pandemic, we saw how hard it was to scale up diagnostic infrastructure,” Gibson says. Diagnostic services in sub-Saharan Africa face “similar challenges, but in a much poorer setting.”

      In Malawi, sample transportation is managed by a  nongovernment organization called Riders 4 Health. The organization has around 80 couriers on motorcycles who transport samples and test results between facilities. “When we started working with [Riders], the couriers operated on fixed weekly schedules, visiting each site once or twice a week,” Gibson says. But that led to “a lot of unnecessary trips and delays.”

      To make sample transportation more efficient, Gibson developed a dynamic scheduling system that adapts to the current demand for diagnostic testing. The system consists of two main parts: an information sharing platform that aggregates sample transportation data, and an algorithm that uses the data to generate optimized routes and schedules for sample transport couriers.

      In 2019, Gibson ran a four-month-long pilot test for this system in three out of the 27 districts in Malawi. During the pilot study, six couriers transported over 20,000 samples and results across 51 health care facilities, and 150 health care workers participated in data sharing.

      The pilot was a success. Gibson’s dynamic scheduling system eliminated about half the unnecessary trips and reduced transportation delays by 25 percent — a delay that used to be four days was reduced to three. Now, Riders 4 Health is developing their own version of Gibson’s system to operate nationally in Malawi. Throughout this project, “we focused on making sure this was something that could grow with the organization,” she says. “It’s gratifying to see that actually happening.”

      Leveraging patient data

      Gibson is completing her MIT degree this September but will continue working to improve health care in Africa. After graduation, she will join the technology and analytics health care practice of an established company in South Africa. Her initial focus will be on public health care institutions, including Chris Hani Baragwanath Academic Hospital in Johannesburg, the third-largest hospital in the world.

      In this role, Gibson will work to fill in gaps in African patient data for medical operational research and develop ways to use this data more effectively to improve health care in resource-limited areas. For example, better data systems can help to monitor the prevalence and impact of different diseases, guiding where health care workers and researchers put their efforts to help the most people. “You can’t make good decisions if you don’t have all the information,” Gibson says.

      To best leverage patient data for improving health care, Gibson plans to reevaluate how data systems are structured and used in the hospital. For ideas on upgrading the current system, she’ll look to existing data systems in other countries to see what works and what doesn’t, while also drawing upon her past research experience in U.S. health care. Ultimately, she’ll tailor the new hospital data system to South African needs to accurately inform future directions in health care.

      Gibson’s new job — her “dream job” — will be based in the United Kingdom, but she anticipates spending a significant amount of time in Johannesburg. “I have so many opportunities in the wider world, but the ones that appeal to me are always back in the place I came from,” she says. More