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    Six MIT students selected as spring 2024 MIT-Pillar AI Collective Fellows

    The MIT-Pillar AI Collective has announced six fellows for the spring 2024 semester. With support from the program, the graduate students, who are in their final year of a master’s or PhD program, will conduct research in the areas of AI, machine learning, and data science with the aim of commercializing their innovations.

    Launched by MIT’s School of Engineering and Pillar VC in 2022, the MIT-Pillar AI Collective supports faculty, postdocs, and students conducting research on AI, machine learning, and data science. Supported by a gift from Pillar VC and administered by the MIT Deshpande Center for Technological Innovation, the mission of the program is to advance research toward commercialization.

    The spring 2024 MIT-Pillar AI Collective Fellows are:

    Yasmeen AlFaraj

    Yasmeen AlFaraj is a PhD candidate in chemistry whose interest is in the application of data science and machine learning to soft materials design to enable next-generation, sustainable plastics, rubber, and composite materials. More specifically, she is applying machine learning to the design of novel molecular additives to enable the low-cost manufacturing of chemically deconstructable thermosets and composites. AlFaraj’s work has led to the discovery of scalable, translatable new materials that could address thermoset plastic waste. As a Pillar Fellow, she will pursue bringing this technology to market, initially focusing on wind turbine blade manufacturing and conformal coatings. Through the Deshpande Center for Technological Innovation, AlFaraj serves as a lead for a team developing a spinout focused on recyclable versions of existing high-performance thermosets by incorporating small quantities of a degradable co-monomer. In addition, she participated in the National Science Foundation Innovation Corps program and recently graduated from the Clean Tech Open, where she focused on enhancing her business plan, analyzing potential markets, ensuring a complete IP portfolio, and connecting with potential funders. AlFaraj earned a BS in chemistry from University of California at Berkeley.

    Ruben Castro Ornelas

    Ruben Castro Ornelas is a PhD student in mechanical engineering who is passionate about the future of multipurpose robots and designing the hardware to use them with AI control solutions. Combining his expertise in programming, embedded systems, machine design, reinforcement learning, and AI, he designed a dexterous robotic hand capable of carrying out useful everyday tasks without sacrificing size, durability, complexity, or simulatability. Ornelas’s innovative design holds significant commercial potential in domestic, industrial, and health-care applications because it could be adapted to hold everything from kitchenware to delicate objects. As a Pillar Fellow, he will focus on identifying potential commercial markets, determining the optimal approach for business-to-business sales, and identifying critical advisors. Ornelas served as co-director of StartLabs, an undergraduate entrepreneurship club at MIT, where he earned an BS in mechanical engineering.

    Keeley Erhardt

    Keeley Erhardt is a PhD candidate in media arts and sciences whose research interests lie in the transformative potential of AI in network analysis, particularly for entity correlation and hidden link detection within and across domains. She has designed machine learning algorithms to identify and track temporal correlations and hidden signals in large-scale networks, uncovering online influence campaigns originating from multiple countries. She has similarly demonstrated the use of graph neural networks to identify coordinated cryptocurrency accounts by analyzing financial time series data and transaction dynamics. As a Pillar Fellow, Erhardt will pursue the potential commercial applications of her work, such as detecting fraud, propaganda, money laundering, and other covert activity in the finance, energy, and national security sectors. She has had internships at Google, Facebook, and Apple and held software engineering roles at multiple tech unicorns. Erhardt earned an MEng in electrical engineering and computer science and a BS in computer science, both from MIT.

    Vineet Jagadeesan Nair

    Vineet Jagadeesan Nair is a PhD candidate in mechanical engineering whose research focuses on modeling power grids and designing electricity markets to integrate renewables, batteries, and electric vehicles. He is broadly interested in developing computational tools to tackle climate change. As a Pillar Fellow, Nair will explore the application of machine learning and data science to power systems. Specifically, he will experiment with approaches to improve the accuracy of forecasting electricity demand and supply with high spatial-temporal resolution. In collaboration with Project Tapestry @ Google X, he is also working on fusing physics-informed machine learning with conventional numerical methods to increase the speed and accuracy of high-fidelity simulations. Nair’s work could help realize future grids with high penetrations of renewables and other clean, distributed energy resources. Outside academics, Nair is active in entrepreneurship, most recently helping to organize the 2023 MIT Global Startup Workshop in Greece. He earned an MS in computational science and engineering from MIT, an MPhil in energy technologies from Cambridge University as a Gates Scholar, and a BS in mechanical engineering and a BA in economics from University of California at Berkeley.

    Mahdi Ramadan

    Mahdi Ramadan is a PhD candidate in brain and cognitive sciences whose research interests lie at the intersection of cognitive science, computational modeling, and neural technologies. His work uses novel unsupervised methods for learning and generating interpretable representations of neural dynamics, capitalizing on recent advances in AI, specifically contrastive and geometric deep learning techniques capable of uncovering the latent dynamics underlying neural processes with high fidelity. As a Pillar Fellow, he will leverage these methods to gain a better understanding of dynamical models of muscle signals for generative motor control. By supplementing current spinal prosthetics with generative AI motor models that can streamline, speed up, and correct limb muscle activations in real time, as well as potentially using multimodal vision-language models to infer the patients’ high-level intentions, Ramadan aspires to build truly scalable, accessible, and capable commercial neuroprosthetics. Ramadan’s entrepreneurial experience includes being the co-founder of UltraNeuro, a neurotechnology startup, and co-founder of Presizely, a computer vision startup. He earned a BS in neurobiology from University of Washington.

    Rui (Raymond) Zhou

    Rui (Raymond) Zhou is a PhD candidate in mechanical engineering whose research focuses on multimodal AI for engineering design. As a Pillar Fellow, he will advance models that could enable designers to translate information in any modality or combination of modalities into comprehensive 2D and 3D designs, including parametric data, component visuals, assembly graphs, and sketches. These models could also optimize existing human designs to accomplish goals such as improving ergonomics or reducing drag coefficient. Ultimately, Zhou aims to translate his work into a software-as-a-service platform that redefines product design across various sectors, from automotive to consumer electronics. His efforts have the potential to not only accelerate the design process but also reduce costs, opening the door to unprecedented levels of customization, idea generation, and rapid prototyping. Beyond his academic pursuits, Zhou founded UrsaTech, a startup that integrates AI into education and engineering design. He earned a BS in electrical engineering and computer sciences from University of California at Berkeley. More

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    How symmetry can come to the aid of machine learning

    Behrooz Tahmasebi — an MIT PhD student in the Department of Electrical Engineering and Computer Science (EECS) and an affiliate of the Computer Science and Artificial Intelligence Laboratory (CSAIL) — was taking a mathematics course on differential equations in late 2021 when a glimmer of inspiration struck. In that class, he learned for the first time about Weyl’s law, which had been formulated 110 years earlier by the German mathematician Hermann Weyl. Tahmasebi realized it might have some relevance to the computer science problem he was then wrestling with, even though the connection appeared — on the surface — to be thin, at best. Weyl’s law, he says, provides a formula that measures the complexity of the spectral information, or data, contained within the fundamental frequencies of a drum head or guitar string.

    Tahmasebi was, at the same time, thinking about measuring the complexity of the input data to a neural network, wondering whether that complexity could be reduced by taking into account some of the symmetries inherent to the dataset. Such a reduction, in turn, could facilitate — as well as speed up — machine learning processes.

    Weyl’s law, conceived about a century before the boom in machine learning, had traditionally been applied to very different physical situations — such as those concerning the vibrations of a string or the spectrum of electromagnetic (black-body) radiation given off by a heated object. Nevertheless, Tahmasebi believed that a customized version of that law might help with the machine learning problem he was pursuing. And if the approach panned out, the payoff could be considerable.

    He spoke with his advisor, Stefanie Jegelka — an associate professor in EECS and affiliate of CSAIL and the MIT Institute for Data, Systems, and Society — who believed the idea was definitely worth looking into. As Tahmasebi saw it, Weyl’s law had to do with gauging the complexity of data, and so did this project. But Weyl’s law, in its original form, said nothing about symmetry.

    He and Jegelka have now succeeded in modifying Weyl’s law so that symmetry can be factored into the assessment of a dataset’s complexity. “To the best of my knowledge,” Tahmasebi says, “this is the first time Weyl’s law has been used to determine how machine learning can be enhanced by symmetry.”

    The paper he and Jegelka wrote earned a “Spotlight” designation when it was presented at the December 2023 conference on Neural Information Processing Systems — widely regarded as the world’s top conference on machine learning.

    This work, comments Soledad Villar, an applied mathematician at Johns Hopkins University, “shows that models that satisfy the symmetries of the problem are not only correct but also can produce predictions with smaller errors, using a small amount of training points. [This] is especially important in scientific domains, like computational chemistry, where training data can be scarce.”

    In their paper, Tahmasebi and Jegelka explored the ways in which symmetries, or so-called “invariances,” could benefit machine learning. Suppose, for example, the goal of a particular computer run is to pick out every image that contains the numeral 3. That task can be a lot easier, and go a lot quicker, if the algorithm can identify the 3 regardless of where it is placed in the box — whether it’s exactly in the center or off to the side — and whether it is pointed right-side up, upside down, or oriented at a random angle. An algorithm equipped with the latter capability can take advantage of the symmetries of translation and rotations, meaning that a 3, or any other object, is not changed in itself by altering its position or by rotating it around an arbitrary axis. It is said to be invariant to those shifts. The same logic can be applied to algorithms charged with identifying dogs or cats. A dog is a dog is a dog, one might say, irrespective of how it is embedded within an image. 

    The point of the entire exercise, the authors explain, is to exploit a dataset’s intrinsic symmetries in order to reduce the complexity of machine learning tasks. That, in turn, can lead to a reduction in the amount of data needed for learning. Concretely, the new work answers the question: How many fewer data are needed to train a machine learning model if the data contain symmetries?

    There are two ways of achieving a gain, or benefit, by capitalizing on the symmetries present. The first has to do with the size of the sample to be looked at. Let’s imagine that you are charged, for instance, with analyzing an image that has mirror symmetry — the right side being an exact replica, or mirror image, of the left. In that case, you don’t have to look at every pixel; you can get all the information you need from half of the image — a factor of two improvement. If, on the other hand, the image can be partitioned into 10 identical parts, you can get a factor of 10 improvement. This kind of boosting effect is linear.

    To take another example, imagine you are sifting through a dataset, trying to find sequences of blocks that have seven different colors — black, blue, green, purple, red, white, and yellow. Your job becomes much easier if you don’t care about the order in which the blocks are arranged. If the order mattered, there would be 5,040 different combinations to look for. But if all you care about are sequences of blocks in which all seven colors appear, then you have reduced the number of things — or sequences — you are searching for from 5,040 to just one.

    Tahmasebi and Jegelka discovered that it is possible to achieve a different kind of gain — one that is exponential — that can be reaped for symmetries that operate over many dimensions. This advantage is related to the notion that the complexity of a learning task grows exponentially with the dimensionality of the data space. Making use of a multidimensional symmetry can therefore yield a disproportionately large return. “This is a new contribution that is basically telling us that symmetries of higher dimension are more important because they can give us an exponential gain,” Tahmasebi says. 

    The NeurIPS 2023 paper that he wrote with Jegelka contains two theorems that were proved mathematically. “The first theorem shows that an improvement in sample complexity is achievable with the general algorithm we provide,” Tahmasebi says. The second theorem complements the first, he added, “showing that this is the best possible gain you can get; nothing else is achievable.”

    He and Jegelka have provided a formula that predicts the gain one can obtain from a particular symmetry in a given application. A virtue of this formula is its generality, Tahmasebi notes. “It works for any symmetry and any input space.” It works not only for symmetries that are known today, but it could also be applied in the future to symmetries that are yet to be discovered. The latter prospect is not too farfetched to consider, given that the search for new symmetries has long been a major thrust in physics. That suggests that, as more symmetries are found, the methodology introduced by Tahmasebi and Jegelka should only get better over time.

    According to Haggai Maron, a computer scientist at Technion (the Israel Institute of Technology) and NVIDIA who was not involved in the work, the approach presented in the paper “diverges substantially from related previous works, adopting a geometric perspective and employing tools from differential geometry. This theoretical contribution lends mathematical support to the emerging subfield of ‘Geometric Deep Learning,’ which has applications in graph learning, 3D data, and more. The paper helps establish a theoretical basis to guide further developments in this rapidly expanding research area.” More

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    Generating the policy of tomorrow

    As first-year students in the Social and Engineering Systems (SES) doctoral program within the MIT Institute for Data, Systems, and Society (IDSS), Eric Liu and Ashely Peake share an interest in investigating housing inequality issues.

    They also share a desire to dive head-first into their research.

    “In the first year of your PhD, you’re taking classes and still getting adjusted, but we came in very eager to start doing research,” Liu says.

    Liu, Peake, and many others found an opportunity to do hands-on research on real-world problems at the MIT Policy Hackathon, an initiative organized by students in IDSS, including the Technology and Policy Program (TPP). The weekend-long, interdisciplinary event — now in its sixth year — continues to gather hundreds of participants from around the globe to explore potential solutions to some of society’s greatest challenges.

    This year’s theme, “Hack-GPT: Generating the Policy of Tomorrow,” sought to capitalize on the popularity of generative AI (like the chatbot ChatGPT) and the ways it is changing how we think about technical and policy-based challenges, according to Dansil Green, a second-year TPP master’s student and co-chair of the event.

    “We encouraged our teams to utilize and cite these tools, thinking about the implications that generative AI tools have on their different challenge categories,” Green says.

    After 2022’s hybrid event, this year’s organizers pivoted back to a virtual-only approach, allowing them to increase the overall number of participants in addition to increasing the number of teams per challenge by 20 percent.

    “Virtual allows you to reach more people — we had a high number of international participants this year — and it helps reduce some of the costs,” Green says. “I think going forward we are going to try and switch back and forth between virtual and in-person because there are different benefits to each.”

    “When the magic hits”

    Liu and Peake competed in the housing challenge category, where they could gain research experience in their actual field of study. 

    “While I am doing housing research, I haven’t necessarily had a lot of opportunities to work with actual housing data before,” says Peake, who recently joined the SES doctoral program after completing an undergraduate degree in applied math last year. “It was a really good experience to get involved with an actual data problem, working closer with Eric, who’s also in my lab group, in addition to meeting people from MIT and around the world who are interested in tackling similar questions and seeing how they think about things differently.”

    Joined by Adrian Butterton, a Boston-based paralegal, as well as Hudson Yuen and Ian Chan, two software engineers from Canada, Liu and Peake formed what would end up being the winning team in their category: “Team Ctrl+Alt+Defeat.” They quickly began organizing a plan to address the eviction crisis in the United States.

    “I think we were kind of surprised by the scope of the question,” Peake laughs. “In the end, I think having such a large scope motivated us to think about it in a more realistic kind of way — how could we come up with a solution that was adaptable and therefore could be replicated to tackle different kinds of problems.”

    Watching the challenge on the livestream together on campus, Liu says they immediately went to work, and could not believe how quickly things came together.

    “We got our challenge description in the evening, came out to the purple common area in the IDSS building and literally it took maybe an hour and we drafted up the entire project from start to finish,” Liu says. “Then our software engineer partners had a dashboard built by 1 a.m. — I feel like the hackathon really promotes that really fast dynamic work stream.”

    “People always talk about the grind or applying for funding — but when that magic hits, it just reminds you of the part of research that people don’t talk about, and it was really a great experience to have,” Liu adds.

    A fresh perspective

    “We’ve organized hackathons internally at our company and they are great for fostering innovation and creativity,” says Letizia Bordoli, senior AI product manager at Veridos, a German-based identity solutions company that provided this year’s challenge in Data Systems for Human Rights. “It is a great opportunity to connect with talented individuals and explore new ideas and solutions that we might not have thought about.”

    The challenge provided by Veridos was focused on finding innovative solutions to universal birth registration, something Bordoli says only benefited from the fact that the hackathon participants were from all over the world.

    “Many had local and firsthand knowledge about certain realities and challenges [posed by the lack of] birth registration,” Bordoli says. “It brings fresh perspectives to existing challenges, and it gave us an energy boost to try to bring innovative solutions that we may not have considered before.”

    New frontiers

    Alongside the housing and data systems for human rights challenges was a challenge in health, as well as a first-time opportunity to tackle an aerospace challenge in the area of space for environmental justice.

    “Space can be a very hard challenge category to do data-wise since a lot of data is proprietary, so this really developed over the last few months with us having to think about how we could do more with open-source data,” Green explains. “But I am glad we went the environmental route because it opened the challenge up to not only space enthusiasts, but also environment and climate people.”

    One of the participants to tackle this new challenge category was Yassine Elhallaoui, a system test engineer from Norway who specializes in AI solutions and has 16 years of experience working in the oil and gas fields. Elhallaoui was a member of Team EcoEquity, which proposed an increase in policies supporting the use of satellite data to ensure proper evaluation and increase water resiliency for vulnerable communities.

    “The hackathons I have participated in in the past were more technical,” Elhallaoui says. “Starting with [MIT Science and Technology Policy Institute Director Kristen Kulinowski’s] workshop about policy writers and the solutions they came up with, and the analysis they had to do … it really changed my perspective on what a hackathon can do.”

    “A policy hackathon is something that can make real changes in the world,” she adds. More

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    Blueprint Labs launches a charter school research collaborative

    Over the past 30 years, charter schools have emerged as a prominent yet debated public school option. According to the National Center for Education Statistics, 7 percent of U.S. public school students were enrolled in charter schools in 2021, up from 4 percent in 2010. Amid this expansion, families and policymakers want to know more about charter school performance and its systemic impacts. While researchers have evaluated charter schools’ short-term effects on student outcomes, significant knowledge gaps still exist. 

    MIT Blueprint Labs aims to fill those gaps through its Charter School Research Collaborative, an initiative that brings together practitioners, policymakers, researchers, and funders to make research on charter schools more actionable, rigorous, and efficient. The collaborative will create infrastructure to streamline and fund high-quality, policy-relevant charter research. 

    Joshua Angrist, MIT Ford Professor of Economics and a Blueprint Labs co-founder and director, says that Blueprint Labs hopes “to increase [its] impact by working with a larger group of academic and practitioner partners.” A nonpartisan research lab, Blueprint’s mission is to produce the most rigorous evidence possible to inform policy and practice. Angrist notes, “The debate over charter schools is not always fact-driven. Our goal at the lab is to bring convincing evidence into these discussions.”

    Collaborative kickoff

    The collaborative launched with a two-day kickoff in November. Blueprint Labs welcomed researchers, practitioners, funders, and policymakers to MIT to lay the groundwork for the collaborative. Over 80 participants joined the event, including leaders of charter school organizations, researchers at top universities and institutes, and policymakers and advocates from a variety of organizations and education agencies. 

    Through a series of panels, presentations, and conversations, participants including Rhode Island Department of Education Commissioner Angélica Infante-Green, CEO of Noble Schools Constance Jones, former Knowledge is Power Program CEO Richard Barth, president and CEO of National Association of Charter School Authorizers Karega Rausch, and many others discussed critical topics in the charter school space. These conversations influenced the collaborative’s research agenda. 

    Several sessions also highlighted how to ensure that the research process includes diverse voices to generate actionable evidence. Panelists noted that researchers should be aware of the demands placed on practitioners and should carefully consider community contexts. In addition, collaborators should treat each other as equal partners. 

    Parag Pathak, the Class of 1922 Professor of Economics at MIT and a Blueprint Labs co-founder and director, explained the kickoff’s aims. “One of our goals today is to begin to forge connections between [attendees]. We hope that [their] conversations are the launching point for future collaborations,” he stated. Pathak also shared the next steps for the collaborative: “Beginning next year, we’ll start investing in new research using the agenda [developed at this event] as our guide. We will also support new partnerships between researchers and practitioners.”

    Research agenda

    The discussions at the kickoff informed the collaborative’s research agenda. A recent paper summarizing existing lottery-based research on charter school effectiveness by Sarah Cohodes, an associate professor of public policy at the University of Michigan, and Susha Roy, an associate policy researcher at the RAND Corp., also guides the agenda. Their review finds that in randomized evaluations, many charter schools increase students’ academic achievement. However, researchers have not yet studied charter schools’ impacts on long-term, behavioral, or health outcomes in depth, and rigorous, lottery-based research is currently limited to a handful of urban centers. 

    The current research agenda focuses on seven topics:

    the long-term effects of charter schools;
    the effect of charters on non-test score outcomes;
    which charter school practices have the largest effect on performance;
    how charter performance varies across different contexts;
    how charter school effects vary with demographic characteristics and student background;
    how charter schools impact non-student outcomes, like teacher retention; and
    how system-level factors, such as authorizing practices, impact charter school performance.
    As diverse stakeholders’ priorities continue to shift and the collaborative progresses, the research agenda will continue to evolve.

    Information for interested partners

    Opportunities exist for charter leaders, policymakers, researchers, and funders to engage with the collaborative. Stakeholders can apply for funding, help shape the research agenda, and develop new research partnerships. A competitive funding process will open this month.

    Those interested in receiving updates on the collaborative can fill out this form. Please direct questions to chartercollab@mitblueprintlabs.org. More

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    New hope for early pancreatic cancer intervention via AI-based risk prediction

    The first documented case of pancreatic cancer dates back to the 18th century. Since then, researchers have undertaken a protracted and challenging odyssey to understand the elusive and deadly disease. To date, there is no better cancer treatment than early intervention. Unfortunately, the pancreas, nestled deep within the abdomen, is particularly elusive for early detection. 

    MIT Computer Science and Artificial Intelligence Laboratory (CSAIL) scientists, alongside Limor Appelbaum, a staff scientist in the Department of Radiation Oncology at Beth Israel Deaconess Medical Center (BIDMC), were eager to better identify potential high-risk patients. They set out to develop two machine-learning models for early detection of pancreatic ductal adenocarcinoma (PDAC), the most common form of the cancer. To access a broad and diverse database, the team synced up with a federated network company, using electronic health record data from various institutions across the United States. This vast pool of data helped ensure the models’ reliability and generalizability, making them applicable across a wide range of populations, geographical locations, and demographic groups.

    The two models — the “PRISM” neural network, and the logistic regression model (a statistical technique for probability), outperformed current methods. The team’s comparison showed that while standard screening criteria identify about 10 percent of PDAC cases using a five-times higher relative risk threshold, Prism can detect 35 percent of PDAC cases at this same threshold. 

    Using AI to detect cancer risk is not a new phenomena — algorithms analyze mammograms, CT scans for lung cancer, and assist in the analysis of Pap smear tests and HPV testing, to name a few applications. “The PRISM models stand out for their development and validation on an extensive database of over 5 million patients, surpassing the scale of most prior research in the field,” says Kai Jia, an MIT PhD student in electrical engineering and computer science (EECS), MIT CSAIL affiliate, and first author on an open-access paper in eBioMedicine outlining the new work. “The model uses routine clinical and lab data to make its predictions, and the diversity of the U.S. population is a significant advancement over other PDAC models, which are usually confined to specific geographic regions, like a few health-care centers in the U.S. Additionally, using a unique regularization technique in the training process enhanced the models’ generalizability and interpretability.” 

    “This report outlines a powerful approach to use big data and artificial intelligence algorithms to refine our approach to identifying risk profiles for cancer,” says David Avigan, a Harvard Medical School professor and the cancer center director and chief of hematology and hematologic malignancies at BIDMC, who was not involved in the study. “This approach may lead to novel strategies to identify patients with high risk for malignancy that may benefit from focused screening with the potential for early intervention.” 

    Prismatic perspectives

    The journey toward the development of PRISM began over six years ago, fueled by firsthand experiences with the limitations of current diagnostic practices. “Approximately 80-85 percent of pancreatic cancer patients are diagnosed at advanced stages, where cure is no longer an option,” says senior author Appelbaum, who is also a Harvard Medical School instructor as well as radiation oncologist. “This clinical frustration sparked the idea to delve into the wealth of data available in electronic health records (EHRs).”The CSAIL group’s close collaboration with Appelbaum made it possible to understand the combined medical and machine learning aspects of the problem better, eventually leading to a much more accurate and transparent model. “The hypothesis was that these records contained hidden clues — subtle signs and symptoms that could act as early warning signals of pancreatic cancer,” she adds. “This guided our use of federated EHR networks in developing these models, for a scalable approach for deploying risk prediction tools in health care.”Both PrismNN and PrismLR models analyze EHR data, including patient demographics, diagnoses, medications, and lab results, to assess PDAC risk. PrismNN uses artificial neural networks to detect intricate patterns in data features like age, medical history, and lab results, yielding a risk score for PDAC likelihood. PrismLR uses logistic regression for a simpler analysis, generating a probability score of PDAC based on these features. Together, the models offer a thorough evaluation of different approaches in predicting PDAC risk from the same EHR data.

    One paramount point for gaining the trust of physicians, the team notes, is better understanding how the models work, known in the field as interpretability. The scientists pointed out that while logistic regression models are inherently easier to interpret, recent advancements have made deep neural networks somewhat more transparent. This helped the team to refine the thousands of potentially predictive features derived from EHR of a single patient to approximately 85 critical indicators. These indicators, which include patient age, diabetes diagnosis, and an increased frequency of visits to physicians, are automatically discovered by the model but match physicians’ understanding of risk factors associated with pancreatic cancer. 

    The path forward

    Despite the promise of the PRISM models, as with all research, some parts are still a work in progress. U.S. data alone are the current diet for the models, necessitating testing and adaptation for global use. The path forward, the team notes, includes expanding the model’s applicability to international datasets and integrating additional biomarkers for more refined risk assessment.

    “A subsequent aim for us is to facilitate the models’ implementation in routine health care settings. The vision is to have these models function seamlessly in the background of health care systems, automatically analyzing patient data and alerting physicians to high-risk cases without adding to their workload,” says Jia. “A machine-learning model integrated with the EHR system could empower physicians with early alerts for high-risk patients, potentially enabling interventions well before symptoms manifest. We are eager to deploy our techniques in the real world to help all individuals enjoy longer, healthier lives.” 

    Jia wrote the paper alongside Applebaum and MIT EECS Professor and CSAIL Principal Investigator Martin Rinard, who are both senior authors of the paper. Researchers on the paper were supported during their time at MIT CSAIL, in part, by the Defense Advanced Research Projects Agency, Boeing, the National Science Foundation, and Aarno Labs. TriNetX provided resources for the project, and the Prevent Cancer Foundation also supported the team. More

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    Self-powered sensor automatically harvests magnetic energy

    MIT researchers have developed a battery-free, self-powered sensor that can harvest energy from its environment.

    Because it requires no battery that must be recharged or replaced, and because it requires no special wiring, such a sensor could be embedded in a hard-to-reach place, like inside the inner workings of a ship’s engine. There, it could automatically gather data on the machine’s power consumption and operations for long periods of time.

    The researchers built a temperature-sensing device that harvests energy from the magnetic field generated in the open air around a wire. One could simply clip the sensor around a wire that carries electricity — perhaps the wire that powers a motor — and it will automatically harvest and store energy which it uses to monitor the motor’s temperature.

    “This is ambient power — energy that I don’t have to make a specific, soldered connection to get. And that makes this sensor very easy to install,” says Steve Leeb, the Emanuel E. Landsman Professor of Electrical Engineering and Computer Science (EECS) and professor of mechanical engineering, a member of the Research Laboratory of Electronics, and senior author of a paper on the energy-harvesting sensor.

    In the paper, which appeared as the featured article in the January issue of the IEEE Sensors Journal, the researchers offer a design guide for an energy-harvesting sensor that lets an engineer balance the available energy in the environment with their sensing needs.

    The paper lays out a roadmap for the key components of a device that can sense and control the flow of energy continually during operation.

    The versatile design framework is not limited to sensors that harvest magnetic field energy, and can be applied to those that use other power sources, like vibrations or sunlight. It could be used to build networks of sensors for factories, warehouses, and commercial spaces that cost less to install and maintain.

    “We have provided an example of a battery-less sensor that does something useful, and shown that it is a practically realizable solution. Now others will hopefully use our framework to get the ball rolling to design their own sensors,” says lead author Daniel Monagle, an EECS graduate student.

    Monagle and Leeb are joined on the paper by EECS graduate student Eric Ponce.

    John Donnal, an associate professor of weapons and controls engineering at the U.S. Naval Academy who was not involved with this work, studies techniques to monitor ship systems. Getting access to power on a ship can be difficult, he says, since there are very few outlets and strict restrictions as to what equipment can be plugged in.

    “Persistently measuring the vibration of a pump, for example, could give the crew real-time information on the health of the bearings and mounts, but powering a retrofit sensor often requires so much additional infrastructure that the investment is not worthwhile,” Donnal adds. “Energy-harvesting systems like this could make it possible to retrofit a wide variety of diagnostic sensors on ships and significantly reduce the overall cost of maintenance.”

    A how-to guide

    The researchers had to meet three key challenges to develop an effective, battery-free, energy-harvesting sensor.

    First, the system must be able to cold start, meaning it can fire up its electronics with no initial voltage. They accomplished this with a network of integrated circuits and transistors that allow the system to store energy until it reaches a certain threshold. The system will only turn on once it has stored enough power to fully operate.

    Second, the system must store and convert the energy it harvests efficiently, and without a battery. While the researchers could have included a battery, that would add extra complexities to the system and could pose a fire risk.

    “You might not even have the luxury of sending out a technician to replace a battery. Instead, our system is maintenance-free. It harvests energy and operates itself,” Monagle adds.

    To avoid using a battery, they incorporate internal energy storage that can include a series of capacitors. Simpler than a battery, a capacitor stores energy in the electrical field between conductive plates. Capacitors can be made from a variety of materials, and their capabilities can be tuned to a range of operating conditions, safety requirements, and available space.

    The team carefully designed the capacitors so they are big enough to store the energy the device needs to turn on and start harvesting power, but small enough that the charge-up phase doesn’t take too long.

    In addition, since a sensor might go weeks or even months before turning on to take a measurement, they ensured the capacitors can hold enough energy even if some leaks out over time.

    Finally, they developed a series of control algorithms that dynamically measure and budget the energy collected, stored, and used by the device. A microcontroller, the “brain” of the energy management interface, constantly checks how much energy is stored and infers whether to turn the sensor on or off, take a measurement, or kick the harvester into a higher gear so it can gather more energy for more complex sensing needs.

    “Just like when you change gears on a bike, the energy management interface looks at how the harvester is doing, essentially seeing whether it is pedaling too hard or too soft, and then it varies the electronic load so it can maximize the amount of power it is harvesting and match the harvest to the needs of the sensor,” Monagle explains.

    Self-powered sensor

    Using this design framework, they built an energy management circuit for an off-the-shelf temperature sensor. The device harvests magnetic field energy and uses it to continually sample temperature data, which it sends to a smartphone interface using Bluetooth.

    The researchers used super-low-power circuits to design the device, but quickly found that these circuits have tight restrictions on how much voltage they can withstand before breaking down. Harvesting too much power could cause the device to explode.

    To avoid that, their energy harvester operating system in the microcontroller automatically adjusts or reduces the harvest if the amount of stored energy becomes excessive.

    They also found that communication — transmitting data gathered by the temperature sensor — was by far the most power-hungry operation.

    “Ensuring the sensor has enough stored energy to transmit data is a constant challenge that involves careful design,” Monagle says.

    In the future, the researchers plan to explore less energy-intensive means of transmitting data, such as using optics or acoustics. They also want to more rigorously model and predict how much energy might be coming into a system, or how much energy a sensor might need to take measurements, so a device could effectively gather even more data.

    “If you only make the measurements you think you need, you may miss something really valuable. With more information, you might be able to learn something you didn’t expect about a device’s operations. Our framework lets you balance those considerations,” Leeb says.  

    “This paper is well-documented regarding what a practical self-powered sensor node should internally entail for realistic scenarios. The overall design guidelines, particularly on the cold-start issue, are very helpful,” says Jinyeong Moon, an assistant professor of electrical and computer engineering at Florida State University College of Engineering who was not involved with this work. “Engineers planning to design a self-powering module for a wireless sensor node will greatly benefit from these guidelines, easily ticking off traditionally cumbersome cold-start-related checklists.”

    The work is supported, in part, by the Office of Naval Research and The Grainger Foundation. More

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    3 Questions: Renaud Fournier on transforming MIT’s digital landscape

    Renaud Fournier SM ’95 joined the Institute in September 2023 in the newly established role of chief officer for business and digital transformation and is leading a team focused on simplifying business operations and systems for the MIT community. Fournier has extensive experience implementing systems and solving data challenges, both in higher education and the private sector — most recently, leading the digital transformation effort at New York University. Here, Fournier speaks about how he and his team will work closely with members of the MIT community to chart a course for MIT’s digital evolution.

    Q: What are MIT’s enterprise systems and how are they challenging for our community?

    A: The MIT community relies on our enterprise systems for a range of activities — everything from hiring and evaluating employees to managing research grants and facilities projects to maintaining student information. SAP is our current enterprise resource planning system for human resources, finance, and facilities management, and it’s integrated with other systems that provide additional business functionality. Some of these systems are purchased, like Coupa, while others are partially or fully homegrown, like Kuali Coeus and NIMBUS. Along with SAP, our other core systems — for example, Advance and MITSIS — feed data into a central data warehouse to support reporting.

    MIT’s enterprise systems and data landscape has evolved organically over 30 years. The Institute has become considerably more complicated since then, and they no longer represent the best practices or technology in the IT market.

    Q: What digital transformation projects are you most focused on?

    A: Our primary goal is to free up our community’s time so that they can achieve their greatest impact. The vision is to create easy-to-use and well-integrated systems, along with comprehensible and accessible data for reporting and analysis. To accomplish this, we will be taking a series of actions. These include modernizing our enterprise systems and data architecture to take advantage of better technology and functionality, within a cohesive and well-integrated landscape, and simplifying our business processes. To make our data accessible and actionable, we will implement more robust data governance, assigning clear ownership and accountability. And we will offer IT support that enables our community to accomplish its objectives. We need to address systems, processes, data, and support holistically, while engaging and assisting our community every step of the way.    

    Q: What are your next steps?

    A: Over the next few months, I will be building a team to guide the community on this journey, in partnership with IS&T [Information Systems and Technology], other central units, and our academic areas. Together, we will be developing a thoughtful and actionable multi-year roadmap of digital transformation projects, which will help us to produce a steady stream of improvements for our community. We have not selected any systems yet or determined the order in which they will be implemented. Engagement with stakeholders from central, academic, and research areas will inform how we prioritize projects over the next few years. Once we have created the roadmap to guide us, we look forward to the next phase — getting started on the work itself. More

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    Bridging the gap between preschool policy, practice, and research

    Preschool in the United States has grown dramatically in the past several decades. From 1970 to 2018, preschool enrollment increased from 38 percent to 64 percent of eligible students. Fourteen states are currently discussing preschool expansion, with seven likely to pass some form of universal eligibility within the next calendar year. Amid this expansion, families, policymakers, and practitioners want to better understand preschools’ impacts and the factors driving preschool quality. 

    To address these and other questions, MIT Blueprint Labs recently held a Preschool Research Convening that brought researchers, funders, practitioners, and policymakers to Nashville, Tennessee, to discuss the future of preschool research. Parag Pathak, the Class of 1922 Professor of Economics at MIT and a Blueprint Labs co-founder and director, opened by sharing the goals of the convening: “Our goals for the next two days are to identify pressing, unanswered research questions and connect researchers, practitioners, policymakers, and funders. We also hope to craft a compelling research agenda.”

    Pathak added, “Given preschool expansion nationwide, we believe now is the moment to centralize our efforts and create knowledge to inform pressing decisions. We aim to generate rigorous preschool research that will lead to higher-quality and more equitable preschool.”

    Over 75 participants hailing from universities, early childhood education organizations, school districts, state education departments, and national policy organizations attended the convening, held Nov. 13-14. Through panels, presentations, and conversations, participants discussed essential subjects in the preschool space, built the foundations for valuable partnerships, and formed an actionable and inclusive research agenda.

    Research presented

    Among research works presented was a recent paper by Blueprint Labs affiliate Jesse Bruhn, an assistant professor of economics at Brown University and co-author Emily Emick, also of Brown, reviewing the state of lottery-based preschool research. They found that random evaluations from the past 60 years demonstrate that preschool improves children’s short-run academic outcomes, but those effects fade over time. However, positive impacts re-emerge in the long term through improved outcomes like high school graduation and college enrollment. Limited rigorous research studies children’s behavioral outcomes or the factors that lead to high-quality preschool, though trends from preliminary research suggest that full-day programs, language immersion programs, and specific curricula may benefit children.  

    An earlier Blueprint Labs study that was also presented at the convening is the only recent lottery-based study to provide insight on preschool’s long-term impacts. The work, conducted by Pathak and two others, reveals that enrolling in Boston Public Schools’ universal preschool program boosts children’s likelihood of graduating high school and enrolling in college. Yet, the preschool program had little detectable impact on elementary, middle, and high school state standardized test scores. Students who attended Boston preschool were less likely to be suspended or incarcerated in high school. However, research on preschool’s impacts on behavioral outcomes is limited; it remains an important area for further study. Future work could also fill in other gaps in research, such as access, alternative measures of student success, and variation across geographic contexts and student populations.

    More data sought

    State policy leaders also spoke at the event, including Lisa Roy, executive director of the Colorado Department of Early Childhood, and Sarah Neville-Morgan, deputy superintendent in the Opportunities for All Branch at the California Department of Education. Local practitioners, such as Elsa Holguín, president and CEO of the Denver Preschool Program, and Kristin Spanos, CEO of First 5 Alameda County, as well as national policy leaders including Lauren Hogan, managing director of policy and professional advancement at the National Association for the Education of Young Children, also shared their perspectives. 

    In panel discussions held throughout the kickoff, practitioners, policymakers, and researchers shared their perspectives on pressing questions for future research, including: What practices define high-quality preschool? How does preschool affect family systems and the workforce? How can we expand measures of effectiveness to move beyond traditional assessments? What can we learn from preschool’s differential impacts across time, settings, models, and geographies?

    Panelists also discussed the need for reliable data, sharing that “the absence of data allows the status quo to persist.” Several sessions focused on involving diverse stakeholders in the research process, highlighting the need for transparency, sensitivity to community contexts, and accessible communication about research findings.

    On the second day of the Preschool Research Convening, Pathak shared with attendees, “One of our goals… is to forge connections between all of you in this room and support new partnerships between researchers and practitioners. We hope your conversations are the launching pad for future collaborations.” Jason Sachs, the deputy director of early learning at the Bill and Melinda Gates Foundation and former director of early childhood at Boston Public Schools, provided closing remarks.

    The convening laid the groundwork for a research agenda and new research partnerships that can help answer questions about what works, in what context, for which kids, and under which conditions. Answers to these questions will be fundamental to ensure preschool expands in the most evidence-informed and equitable way possible.

    With this goal in mind, Blueprint Labs aims to create a new Preschool Research Collaborative to equip practitioners, policymakers, funders, and researchers with rigorous, actionable evidence on preschool performance. Pathak states, “We hope this collaborative will foster evidence-based decision-making that improves children’s short- and long-term outcomes.” The connections and research agenda formed at the Preschool Research Convening are the first steps toward achieving that goal. More